DNA binding affinity of bisguanidine and bis (2-aminoimidazoline) derivatives with in vivo antitrypanosomal activity (Publications)
A new antitrypanosomal hit compound that cures an acute (STIB 900) mouse model of Trypanosoma brucei rhodesiense trypanosomiasis is described. This bis(2-aminoimidazolinium) dicationic compound proved
Disesquiterpene and sesquiterpene coumarins from <em>Ferula pseudalliacea</em>, and determination of their absolute configurations (Publications)
The first disesquiterpene coumarin, sanandajin, five sesquiterpene coumarins, kamolonol acetate, fekrynol acetate, ethyl galbanate, methyl galbanate, farnesiferol B, and a sesquiterpene, aristolone, w
Sexual compatibility among <em>Trypanosoma brucei</em> isolates from an epidemic area in southeastern Uganda (Publications)
For the first time, two clones of Trypanosoma brucei from the same epidemic area in southeastern Uganda were successfully crossed. The cotransmission experiments were as close to natural conditions as
Short Message Service (SMS) applications for disease prevention in developing countries (Publications)
BACKGROUND: The last decade has witnessed unprecedented growth in the number of mobile phones in the developing world, thus linking millions of previously unconnected people. The ubiquity of mobile ph
Molecular fingerprinting of the fecal microbiota of children raised according to different lifestyles (Publications)
In this population-based study, 90 children from three European countries were examined to determine the impact of lifestyle on the fecal microbiota. The study was designed to assess the impact of two
Improving health through policies that promote active travel: A review of evidence to support integrated health impact assessment (Publications)
BACKGROUND: Substantial policy changes to control obesity, limit chronic disease, and reduce air pollution emissions, including greenhouse gasses, have been recommended. Transportation and planning po
IGF1 genotype, mean plasma level and breast cancer risk in the Hawaii/Los Angeles multiethnic cohort (Publications)
The insulin-like growth factor 1 gene (IGF1) is a strong candidate gene for a breast cancer susceptibility model. We investigated a dinucleotide repeat 969 bp upstream from the transcription start sit
Identification of <em>Staphylococcus intermedius</em> group by MALDI-TOF MS (Publications)
The Staphylococcus intermedius Group includes S. intermedius, S. pseudintermedius and S. delphini, coagulase-positive bacteria commonly isolated from animals. The identification of organisms belonging
First clinical trial of purified, irradiated malaria sporozoites in humans (Publications)
Evaluation of: Epstein JE, Tewari K, Lyke KE et al. Live attenuated malaria vaccine designed to protect through hepatic CD8 T cell immunity. Science 334(6055), 475-480 (2011). Purified, irradiated, me