Precursor-directed diversification of cyclic tetrapeptidic pseudoxylallemycins (Publications)
Cyclic peptides containing non-proteinogenic amino acids often exhibit a broad bioactivity spectrum and many have entered clinical trials with good prospects for drug development. We recently reported
Mathematical modelling of the impact of expanding levels of malaria control interventions on <em>Plasmodium vivax</em> (Publications)
Plasmodium vivax poses unique challenges for malaria control and elimination, notably the potential for relapses to maintain transmission in the face of drug-based treatment and vector control strateg
C-H activation enables a concise total synthesis of quinine and analogues with enhanced antimalarial activity (Publications)
We report a novel approach to the classical natural product quinine that is based on two stereoselective key steps, namely a C-H activation and an aldol reaction, to unite the two heterocyclic moietie
Full-chain health impact assessment of traffic-related air pollution and childhood asthma (Publications)
BACKGROUND: Asthma is the most common chronic disease in children. Traffic-related air pollution (TRAP) may be an important exposure contributing to its development. In the UK, Bradford is a deprived
Emergency Medical Service (EMS) utilization by Syrian refugees residing in Ankara, Turkey (Publications)
Introduction Many Syrians have left their country and migrated to other countries since March 2011, due to the civil war. As of March 2016, a total of 2,747,946 Syrian refugees had immigrated to Turke
Effects of intensive use of computers in secondary school on gender differences in attitudes towards ICT: a systematic review (Publications)
There is a wealth of interventions focusing on the intensive use of computers in secondary schools, largely aiming at improving students' performance. However, global evidence on the effects of the us