Nanomimics of host cell membranes block invasion and expose invasive malaria parasites (Publications)
The fight against most infectious diseases, including malaria, is often hampered by the emergence of drug resistance and lack or limited efficacies of vaccines. Therefore, new drugs, vaccines, or other [...] ligands involved in the initial attachment to host cells and they efficiently blocked reinvasion of malaria parasites after their egress from host cells in vitro. They exhibited efficacies of more than 2 orders [...] infective parasite. In the future, our strategy might offer interesting...
Encouraging impact following 2.5 years of reinforced malaria control interventions in a hyperendemic region of the Republic of Guinea (Publications)
multi-component malaria control intervention significantly reduced the prevalence of malaria in the sous-prefectures of intervention while also increasing the coverage of bed nets. However, malaria prevalence [...] BACKGROUND: Malaria is one of the principal causes of morbidity and mortality in the Republic of Guinea, particularly in the highly endemic regions. To assist in malaria control efforts, a multi-component [...] nent malaria control intervention was implemented in the hyperendemic...
Basel gegen Malaria : hinter den Kulissen der grössten humanitären Aktion der Schweiz [TV Broadcast] (Publications)
"Basel im Kampf gegen Malaria. Die humanitären Leistungen der letzten Jahre aus Basel im Kampf gegen Malaria stellen alle schweizerischen Anstrengungen für Menschen im zweiten Weltkrieg in den Schatten [...] Tropenkrankheit ist längst nicht ausgestanden. Noch immer sterben jährlich eine Million Menschen an Malaria. Der neue Report widmet sich einer der grössten humanitären Erfolgsgeschichten der Schweiz."
Endlich: Die Malaria-Impfung kommt [TV Broadcast] (Publications)
"Bill Gates selbst gibt am Gates Malaria Forum in Seattle die bahnbrechende Nachricht bekannt: Erstmals im 100-jährigen Kampf gegen Malaria kann die Registrierung eines Impfstoffs eingeleitet werden. Schon [...] Schon bald können also Säuglinge in Malaria-Gebieten routinemässig gegen den lebensbedrohlichen Erreger geimpft und Millionen Menschenleben gerettet werden. Einer freut sich besonders über den Durchbruch: [...] Durchbruch: Der Schweizer Marcel Tanner, unermüdlicher Kämpfer gegen Malaria...
The effect of iron-fortified complementary food and intermittent preventive treatment of malaria on anaemia in 12- to 36-month-old children: a... (Publications)
BACKGROUND: Iron deficiency (ID) and malaria co-exist in tropical regions and both contribute to high rates of anaemia in young children. It is unclear whether iron fortification combined with intermittent [...] intermittent preventive treatment (IPT) of malaria would be an efficacious strategy for reducing anaemia in young children. METHODS: A 9-month cluster-randomised, single-blinded, placebo-controlled intervention [...] out in children aged 12-36 months in south-central Cote d'Ivoire, an...
Safety and efficacy of the RTS,S/AS01(E) candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a... (Publications)
0012) against first malaria episodes and 59% (36-74; p=0.0001) against all malaria episodes. For the entire study period, (total vaccinated cohort) vaccine efficacy against all malaria episodes was higher [...] BACKGROUND: The RTS,S/AS01(E) candidate malaria vaccine is being developed for immunisation of infants in Africa through the expanded programme on immunisation (EPI). 8 month follow-up data have been reported [...] did a randomised, open-label, phase 2 trial of safety and efficacy of the...
