Impact of malaria pre-exposure on anti-parasite cellular and humoral immune responses after controlled human malaria infection (Publications)
understand the effect of previous malaria exposure on anti-parasite immune responses is important for developing successful immunization strategies. Controlled human malaria infections (CHMI) using cryopreserved [...] sporozoites provide a unique opportunity to study differences in acquisition or re-call of anti-malaria immune responses in individuals from different transmission settings and genetic backgrounds. In [...] In this study, we compared anti-parasite humoral and cellular immune...
Appropriating "malaria": local responses to malaria treatment and prevention in Abidjan, Côte d'Ivoire (Publications)
its prevention and control. Malaria is referred to locally as palu, reflecting the incorporation of malaria into a local illness taxonomy. Although the labeling of malaria-related symptoms as palu has [...] relationship to malaria, with implications in the management of the disease. Ethnographic research was conducted from 2003-2005 in urban Abidjan, Cote d'Ivoire, on community understandings of malaria and the [...] appropriation of concepts and material objects, we examine the processes of...
Patterns of human exposure to malaria vectors in Zanzibar and implications for malaria elimination efforts (Publications)
study for malaria elimination. The islands have experienced a dramatic reduction in malaria burden since the introduction of effective vector control interventions and case management. Malaria prevalence [...] sleep. Supplemental interventions targeting outdoor exposure to malaria vectors, and groups that may be at increased risk of exposure to malaria vectors, should be explored. [...] for elimination. METHODS: To better understand factors that may contribute to remaining low-level malaria...
Rapid diagnostic test-based management of malaria: an effectiveness study in Papua New Guinean infants with <em>Plasmodium falciparum</em> and... (Publications)
Background. In malaria-endemic areas it is recommended that febrile children be tested for malaria by rapid diagnostic test (RDT) or blood slide (BS) and receive effective malaria treatment only if results [...] P. vivax malaria on the basis of RDT but BSs were negative; 16 had LRTIs; 3 had alternative diagnoses. Of these 24, 22 were cured at day 28. Two children died of illnesses other than malaria and were RDT [...] RDT and BS negative at the initial and subsequent visits.Conclusion. Treatment...