Impact of malaria pre-exposure on anti-parasite cellular and humoral immune responses after controlled human malaria infection (Publications)
understand the effect of previous malaria exposure on anti-parasite immune responses is important for developing successful immunization strategies. Controlled human malaria infections (CHMI) using cryopreserved [...] sporozoites provide a unique opportunity to study differences in acquisition or re-call of anti-malaria immune responses in individuals from different transmission settings and genetic backgrounds. In [...] In this study, we compared anti-parasite humoral and cellular immune...
Intravenous artesunate reduces parasite clearance time, duration of intensive care and hospital treatment in patients with severe malaria in Europe:... (Publications)
Intravenous artesunate improves survival in severe malaria, but clinical trial data from non-endemic countries are scarce. The TropNet severe malaria database was analyzed to compare outcomes of artesunate [...] clearance time, duration of ICU- and hospital treatment in European patients with imported severe malaria
Disparities of <em>Plasmodium falciparum</em> infection, malaria-related morbidity and access to malaria prevention and treatment among school-aged... (Publications)
There is limited knowledge on the malaria burden of school-aged children in Cote d'Ivoire. The aim of this study was to assess Plasmodium falciparum infection, malaria-related morbidity, use of preventive [...] preventive measures and treatment against malaria, and physical access to health structures among school-aged children across Cote d'Ivoire. METHODS: A national, cross-sectional study was designed, consisting [...] were interviewed to determine household socioeconomic status,...
Malaria risk in Nigeria: Bayesian geostatistical modelling of 2010 malaria indicator survey data (Publications)
2010, the National Malaria Control Programme with the support of Roll Back Malaria partners implemented a nationally representative Malaria Indicator Survey (MIS), which assembled malaria burden and control [...] ic predictors of malaria risk. The population adjusted risk estimates ranges from 6.46% in Lagos state to 43.33% in Borno. Interventions appear to not have important effect on malaria risk. The odds of [...] and living in rural areas increases the odds of testing positive to malaria...
Relationship between child survival and malaria transmission: an analysis of the malaria transmission intensity and mortality burden across Africa... (Publications)
relationship between malaria mortality and levels of transmission is unclear. Due to methodological limitations, earlier efforts to assess the linkage have lead to inconclusive results. The malaria transmission [...] assessing the malaria transmission-mortality relation involves more than the knowledge on the performance of interventions and control measures. This relation depends on the levels of malaria endemicity and [...] age and insecticide-treated nets (ITNs), were fitted to assess the...