Methotrexate and aminopterin lack in vivo antimalarial activity against murine malaria species (Publications)
rheumatoid arthritis indicates that it could be safe and efficacious for treating malaria. We sought to establish a murine malaria model to study the mechanism of action and resistance of MTX and its analogue [...] receptor/transport to gain access to cells, their lack of efficacy against the four tested murine malaria species may be the result of inefficiency of drug transport
Synthetic GPI array to study antitoxic malaria response (Publications)
Parasite glycosylphosphatidylinositol (GPI) is an important toxin in malaria disease, and people living in malaria-endemic regions often produce high levels of anti-GPI antibodies. The natural anti-GPI [...] on a synthetic GPI glycan array to correlate anti-GPI antibody levels and protection from severe malaria
Differential var gene expression in children with malaria and antidromic effects on host gene expression (Publications)
Among 62 children with mild malaria, cerebral malaria, or severe malarial anemia, we analyzed the transcription of different var gene types. There was no difference in parasitemia level or body temperature [...] expression pattern was observed in children with cerebral malaria, compared with that in patients in the other 2 groups: children with cerebral malaria had lower expression of the upsA subtype but higher expression
Genotyping Group | Malaria Research at Swiss TPH (Page)
https://www.swisstph.ch/en/about/med/medicines-development/genotyping
National Malaria Control Programs (NMCPs) and research institutes in malaria endemic countries to implement those new assays in routine surveillance, and provide critical evidence for malaria monitoring [...] Evaluation of the Community-based Malaria Surveillance and Response in Rwanda Malaria incidence has considerably reduced in Rwanda in the last 5 years through combined malaria control interventions. Further [...] interventions approach through reactive Community-based Malaria Surveillance...
Malaria Epidemiology and Control | Swiss TPH Research Groups (Page)
https://www.swisstph.ch/en/about/eph/health-interventions/malaria-epidemiology-and-control
Group | Malaria Epidemiology and Control Health Interventions Analytics and Intervention Modelling Malaria Epidemiology and Control In the Malaria Epidemiology and Control group we focus on generating [...] and evidence-based malaria control efforts at national and decentralized level, enhance multi-sectoral action in malaria control, and develop a knowledge management strategy for malaria control in Tanzania [...] Watch here how visualizing malaria case numbers may be useful to target malaria...
World Malaria Day 2024: Work together and accelerate the fight! (Page)
https://www.swisstph.ch/en/impact-stories/world-malaria-day-2024-work-together-and-accelerate-the-fight
Initiative on Malaria (MIM Society) 8th Pan-African Malaria Conference in Kigali, Rwanda, to shape the future strategies of malaria control and elimination. This worldwide biggest conference on malaria is an important [...] challenges and efforts of controlling malaria on the continent. The conference brings together the international malaria community to device better strategies for malaria control and elimination. (MIM Conference [...] from 1980 to 2024. The graph highlights the number of...
Field Malaria Courses in Tanzania and in Lao PDR | Swiss TPH (Page)
https://www.swisstph.ch/en/study-with-us/postgraduate/field-malaria-courses-in-tanzania-and-in-lao-pdr
Field Malaria Courses in Tanzania and in Lao PDR: Four-Week Postgraduate Courses on Malaria Prevention, Control & Elimination Course Description The objectives of the course are to build capacity by r [...] in the field of malaria and to improve skills in time management, presenting and writing research proposals. At the end of the course, the participants should be able to manage malaria issues more effectively [...] articles on malaria issues. To request specific information from the course...