Clinical and laboratory predictors of imported malaria in an outpatient setting: an aid to medical decision making in returning travelers with fever (Publications)
had the highest positive likelihood ratio for a diagnosis of malaria (13.6), followed by thrombopenia (11.0). Posttest probabilities for malaria were 85% with enlarged spleen and 82% with thrombopenia. A [...] information exists to guide clinicians for giving presumptive treatment to returning travelers when malaria is strongly suspected on clinical grounds but laboratory confirmation is not immediately available [...] laboratory predictors of Plasmodium parasitemia. A total of 336...
Functional and structural similarity of Vgamma9Vdelta2 T cells in humans and Aotus monkeys, a primate infection model for <em>Plasmodium falciparum... (Publications)
gammadelta T cells are implicated to play crucial roles during early immune responses to pathogens. A subset of human gammadelta T cells carrying the Vgamma9Vdelta2 TCR recognize small, phosphorylated
First clinical trial of purified, irradiated malaria sporozoites in humans (Publications)
Evaluation of: Epstein JE, Tewari K, Lyke KE et al. Live attenuated malaria vaccine designed to protect through hepatic CD8 T cell immunity. Science 334(6055), 475-480 (2011). Purified, irradiated, me [...] route in humans are warranted to fully explore the potential of purified, attenuated sporozoites for malaria vaccine development
Introducing vouchers for malaria prevention in Ghana and Tanzania: context and adoption of innovation in health systems (Publications)
that are relevant to the scaling up of continuous delivery of insecticide treated nets (ITNs) for malaria prevention. However, specific contextual factors of relevance to ITN delivery have led implementation