Do health workers' preferences influence their practices? Assessment of providers' attitude and personal use of new treatment recommendations for... (Publications)
Tanzania changed malaria treatment policies twice within a decade. First in 2001 chloroquine (CQ) was replaced by sulfadoxine-pyrimethamine (SP) for management of uncomplicated malaria and by late 2006 [...] by enquiring which antimalarial was considered most suitable for the management of uncomplicated malaria for the three patient categories: i) children below 5; ii) older children and adults; and iii) pregnant [...] pregnant women. Practice was ascertained by asking which antimalarial was...
Dynamics of socioeconomic risk factors for neglected tropical diseases and malaria in an armed conflict (Publications)
and assessed the dynamics of socioeconomic risk factors for neglected tropical diseases (NTDs) and malaria. METHODOLOGY: The same standardized and pre-tested questionnaires were administered to the heads [...] anecdotal evidence point toward a relationship between an increased risk of suffering from NTDs and malaria and armed conflict. CONCLUSION: New research is needed to deepen our understanding of the often diffuse
Cell biological characterization of the malaria vaccine candidate trophozoite exported protein 1 (Publications)
extensive preclinical evaluation of its coiled coil peptides Tex1 was identified as promising novel malaria vaccine candidate providing the rational for a comprehensive cell biological characterization of
Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications (Publications)
in the risk of clinical malaria between the second and the third dose; during the same period, there was no significant effect in Manhica. Similarly, protection against malaria episodes was maintained [...] explanation for the difference in IPTi efficacy on clinical malaria. Combination of IPTi and ITNs may be the most cost-effective tool for malaria control currently available, and needs to be explored in current [...] (IPTi) with sulphadoxine-pyrimethamine (SP) in infants resulted in different...
Modern geographical reconnaissance of target populations in malaria elimination zones (Publications)
approaches to GR to define the spatial distribution of target populations to support contemporary malaria elimination interventions. METHODS: Three GR surveys were carried out covering the outer islands [...] priority elimination interventions, including bed net distribution, indoor residual spraying (IRS) and malaria case surveillance. Data were uploaded and analysed in customized Geographic Information System (GIS) [...] operational tool for rapidly defining the spatial distribution of target...
Routine delivery of artemisinin-based combination treatment at fixed health facilities reduces malaria prevalence in Tanzania: an observational study (Publications)
combination therapy (ACT) has been promoted as a means to reduce malaria transmission due to their ability to kill both asexual blood stages of malaria parasites, which sustain infections over long periods and [...] between ACT introduction and reduced malaria transmission in a number of ecological settings. However, these reports have come from areas with low to moderate malaria transmission, been confounded by the [...] the presence of other interventions or environmental changes that may have...
Simplified models of vector control impact upon malaria transmission by zoophagic mosquitoes (Publications)
measures that kill mosquitoes dramatically reduce malaria transmission where vector populations depend upon human blood. However, most primary malaria vectors outside of sub-Saharan Africa can be classified
Social and cultural aspects of 'malaria' and its control in central Côte d'Ivoire (Publications)
behaviour is important for the effective control of malaria. The purpose of this study was to assess the knowledge, attitudes, practices and beliefs of 'malaria' and its control in two rural communities of central [...] employing a household asset-based approach. RESULTS: Malaria was identified as djekouadjo, the local folk name of the disease. Although people were aware of malaria-related symptoms and their association with [...] central Cote d'Ivoire, and to examine associations between 'mala...
A simulation model of African Anopheles ecology and population dynamics for the analysis of malaria transmission (Publications)
BACKGROUND: Malaria is one of the oldest and deadliest infectious diseases in humans. Many mathematical models of malaria have been developed during the past century, and applied to potential interventions [...] However, malaria remains uncontrolled and is increasing in many areas, as are vector and parasite resistance to insecticides and drugs. METHODS: This study presents a simulation model of African malaria vectors