Environmental predictors of the seasonality of malaria transmission in Africa: the challenge (Publications)
A description of malaria seasonality is important for planning and optimizing malaria control in both time and space, but adequate malariologic data are not available for many disease-endemic areas. We [...] between the seasonal dynamics of environmental determinants and malaria pose a great challenge and highlights the need for improved models of malaria seasonality
Epidemiology of malaria in the Papua New Guinean highlands (Publications)
Below 1400 m, malaria was a significant source of febrile illness. At higher altitudes, malaria was only a significant source of febrile illness during epidemic outbreaks, but asymptomatic malaria infections [...] investigation of the epidemiology of malaria in the Papua New Guinea (PNG) highlands and provide a basis for evidence-based planning and monitoring of intensified malaria control activities. Methods Between [...] and July 2005, 153 household-based, rapid malaria population surveys were...
Estimating malaria transmission through mathematical models (Publications)
Evaluating the effectiveness of malaria control interventions on the basis of their impact on transmission is increasingly important as countries move from malaria control to pre-elimination programs. [...] Mathematical modeling can examine relationships between malaria indicators, allowing translation of easily measured data into measures of transmission, and addressing key concerns with traditional methods [...] Simulations show these indicators are statistically correlated, allowing direct...
Optimized Malaria-antigens delivered by immunostimulating reconstituted influenza virosomes (Publications)
Malaria remains a serious cause of morbidity and mortality in millions of individuals each year. The development of widespread resistance of the parasite to drugs as well as resistance of the transmitting [...] transmitting mosquito-vector to insecticides in combination with the poor economic situation of many malaria-endemic countries make the development of an effective and inexpensive treatment and prevention a main [...] appropriate conformation. Here, we review the development of a new...
Cost savings with rapid diagnostic tests for malaria in low-transmission areas: evidence from Dar es Salaam, Tanzania (Publications)
Rapid diagnostic tests (RDTs) for malaria may help rationalize antimalarial drug use. However, the economic effects of these tests may vary. Data on costs were collected from 259 patients in 6 health
High throughput multiplex assay for species identification of Papua New Guinea malaria vectors: members of the <em>Anopheles punctulatus</em>... (Publications)
Malaria and filariasis are transmitted in the Southwest Pacific region by Anopheles punctulatus sibling species including An. punctulatus, An. koliensis, the An. farauti complex 1-8 (includes An. hinesorum