Dietary diversity in primary schoolchildren of south-central Côte d'Ivoire and risk factors for non-communicable diseases (Publications)
prediabetes and malaria infection, as well as medium and high DDS. Overweight was associated with malaria infection and moderate anaemia. CONCLUSION: Overweight, prediabetes, low HDL-C, malaria, and anaemia [...] the primary caretaker according to the guideline of Food and Agriculture Organization. Anaemia, malaria, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and blood [...] health in Taabo. Our findings highlight interactions between infectious...
Comparative efficacy of Vector Guard® to Olyset® Plus insecticide-treated nets against strongly pyrethroid-resistant <em>Anopheles arabiensis</em> in... (Publications)
promising pyrethroid–PBO ITN for the control of resistant malaria vectors. The addition of Vector Guard® to the class of pyrethroid–PBO ITNs will enable malaria control programs to select cost-effective ITNs, improving [...] Introduction: The resistance of malaria vectors to pyrethroids has compromised the efficacy of pyrethroid insecticide-treated nets (ITNs). In response, ITNs with pyrethroids and piperonyl butoxide (PBO) [...] conducted to evaluate Vector Guard® relative to Olyset® Plus (a...
The impact of using primaquine without prior G6PD testing: a case series describing the obstacles to the medical management of haemolysis (Publications)
vivax malaria in glucose-6-phosphate dehydrogenase (G6PD) deficient individuals employs weekly primaquine dosing. This is the only recommended regimen for this patient sub-group. If national malaria programs [...] with unknown G6PD status from two different countries were prescribed primaquine as per national malaria program guidelines. During treatment both patients presented to the clinic with symptoms of anaemia
Antimalarial agents derived from metal-amodiaquine complexes with activity in multiple stages of the <em>Plasmodium</em> life cycle (Publications)
Malaria is the one of the deadliest infectious diseases worldwide. Chemically, quinolines are excellent ligands for metal coordination and are deployed as drugs for malaria treatment. There is a growing [...] coordination with antimalarial quinolines is a potential chemical tool for drug design and discovery in malaria and other infectious diseases susceptible to quinoline treatment.
Artemisinins and synthetic trioxolanes in the treatment of helminth infections (Publications)
following recommended malaria treatment schedules, found an effect against schistosomiasis. SUMMARY: Artemisinin-based combination therapies are increasingly deployed against malaria, and hence there is [...] that artemisinin-based combination therapy might have on trematode infections in settings where malaria and helminthiases are co-endemic. RECENT FINDINGS: The artemisinins and synthetic trioxolanes possess
Artemisinins and synthetic trioxolanes in the treatment of helminth infections (Publications)
following recommended malaria treatment schedules, found an effect against schistosomiasis. SUMMARY: Artemisinin-based combination therapies are increasingly deployed against malaria, and hence there is [...] that artemisinin-based combination therapy might have on trematode infections in settings where malaria and helminthiases are co-endemic. RECENT FINDINGS: The artemisinins and synthetic trioxolanes possess
The impact of using primaquine without prior G6PD testing: a case series describing the obstacles to the medical management of haemolysis (Publications)
vivax malaria in glucose-6-phosphate dehydrogenase (G6PD) deficient individuals employs weekly primaquine dosing. This is the only recommended regimen for this patient sub-group. If national malaria programs [...] with unknown G6PD status from two different countries were prescribed primaquine as per national malaria program guidelines. During treatment both patients presented to the clinic with symptoms of anaemia
Antimalarial agents derived from metal-amodiaquine complexes with activity in multiple stages of the <em>Plasmodium</em> life cycle (Publications)
Malaria is the one of the deadliest infectious diseases worldwide. Chemically, quinolines are excellent ligands for metal coordination and are deployed as drugs for malaria treatment. There is a growing [...] coordination with antimalarial quinolines is a potential chemical tool for drug design and discovery in malaria and other infectious diseases susceptible to quinoline treatment.
Effect of RTS,S/AS01E vaccine booster dose on cellular immune responses in African infants and children (Publications)
RTS,S/AS01(E), the first approved malaria vaccine, demonstrated moderate efficacy during the phase 3 pediatric trial. We previously investigated cell-mediated immune (CMI) responses following the primary [...] from 709 children and infants after RTS,S/AS01(E) antigen stimulation, and their associations with malaria risk and antibodies one month post-booster and one year later were assessed. IL-2, IFN-γ, IL-17, [...] circumsporozoite protein (CSP) remained higher after one year. IL-2 was...
Identification of a potential antimalarial drug candidate from a series of 2-aminopyrazines by optimization of aqueous solubility and potency across... (Publications)
blood life-cycle stage of the human malaria parasite Plasmodium falciparum. Several compounds displayed high in vivo efficacy in two different mouse models for malaria, P. berghei-infected mice and P. f