Force of infection is key to understanding the epidemiology of <em>Plasmodium falciparum</em> malaria in Papua New Guinean children (Publications)
describes basic malaria epidemiology and is suitable for measuring outcomes of interventions. This study was designed to test whether (mol)FOI influenced the risk of clinical malaria episodes and how [...] highlights the suitability of (mol)FOI as a measure of individual exposure and its central role in malaria epidemiology. It has substantial advantages over entomological measures in studies of transmission
Operational strategies to achieve and maintain malaria elimination (Publications)
Present elimination strategies are based on recommendations derived during the Global Malaria Eradication Program of the 1960s. However, many countries considering elimination nowadays have high intrinsic [...] need to revisit the strategies on which contemporary elimination programmes are based. To eliminate malaria, programmes need to concentrate on identification and elimination of foci of infections through both [...] of infectious pools entirely will not be sufficient since they could be...
Human antibodies to recombinant protein constructs of <em>Plasmodium falciparum</em> Apical Membrane Antigen 1 (AMA1) and their associations with... (Publications)
ectodomain (both FVO and 3D7 allele constructs) prior to a malaria transmission season were significantly associated with protection from malaria in the following 6 months, even after adjusting for age and
A need for better housing to further reduce indoor malaria transmission in areas with high bed net coverage (Publications)
: Despite significant reductions in vector density and malaria transmission caused by high coverage of ITNs, high numbers of host-seeking malaria vectors are still found indoors due to house designs that [...] BACKGROUND: The suppression of indoor malaria transmission requires additional interventions that complement the use of insecticide treated nets (ITNs) and indoor residual spraying (IRS). Previous studies [...] studies have examined the impact of house structure on malaria transmission in...
High prevalence of malaria in Zambezia, Mozambique: the protective effect of IRS versus increased risks due to pig-keeping and house construction (Publications)
high in many parts of the continent. This study investigated risk factors for malaria infection in children using three malaria indicator surveys from Zambezia province, Mozambique. The impact of IRS and [...] screened for malaria by rapid diagnostic tests. Caregiver interviews were used to assess household demographic and wealth characteristics and ITN and IRS coverage. Associations between malaria infection, [...] versus small households (1-4 persons). CONCLUSION: Malaria infection among...