Factors influencing the pattern of imported malaria (Publications)
imported malaria in industrialized areas are known to be incomplete because of underreporting and lack of homogeneity. These facts and the complexity of factors influencing the transmission of malaria render [...] duration of stay on the latency of malaria attacks. African origin and repeated stays were confounders with regard to adherence to chemoprophylaxis. The local situation of malaria transmission and the development [...] to influence the evolution of malaria rates. These factors must be...
Asexual blood-stage malaria vaccine development: facing the challenges (Publications)
reduce morbidity. RECENT FINDINGS: There is good rationale to support the development of blood-stage malaria vaccines, the most promising being the demonstration that nonimmune volunteers repeatedly challenged [...] as well as the demonstration of the efficacy of the first asexual blood-stage vaccine tested in a malaria endemic area (combination B) to reduce parasite density in children. The selective pressure induced
Safety and immunogenicity of a three-component blood-stage malaria vaccine (MSP1, MSP2, RESA) against <em>Plasmodium falciparum</em> in Papua New... (Publications)
Combination B is a malaria vaccine that comprises recombinant Plasmodium falciparum (P. falciparum) blood-stage proteins MSP1, MSP2 and RESA, formulated with the adjuvant Montanide ISA 720. A phase I-IIb [...] nor increased after pre-treatment with SP and pre-treatment is not advisable in future trials of malaria vaccines, at least for those including blood-stage antigens
Malaria mapping using transmission models: application to survey data from Mali (Publications)
to age-specific malaria prevalence. The approach makes more efficient use of the available data than do previous malaria mapping methods, and it produces highly plausible maps of malaria distribution [...] Geographic mapping of the distribution of malaria is complicated by the limitations of the available data. The most widely available data are from prevalence surveys, but these surveys are generally carried [...] approach to the analysis of survey data from Mali, collected in 1965-1998,...
Malaria and casual sex: what travelers know and how they behave (Publications)
Results: Compliance with chemosuppressive regimen for malaria was 87%. Well-informed travelers did not protect themselves more efficiently against malaria. The efficacy of a given intervention was found to [...] Background: Travelers to the tropics have been reported to comply poorly with recommendations regarding malaria and AIDS. This study addresses the problem of influencing travelers' behavior through different [...] implications of "sex tourism" and the possibility of participating in a...
Malaria vaccines: from the laboratory to the field (Publications)
cure of malaria patients with passive transfer of specific immunoglobulins, and iii) protection conferred by vaccination with sporozoites attenuated by radiation, justifies the search for a malaria vaccine [...] include recombinant proteins, synthetic peptides and DNA vaccines, the relevant genes encoding malaria antigens being inserted into a plasmid or a live vector such as vaccinia or poxvirus. A number of [...] Combination B) had an efficacy of 62% in reducing parasite density in Papua New...
Exploring the contributions of bed nets, cattle, insecticides and excitorepellency to malaria control: a deterministic model of mosquito host-seeking... (Publications)
Domestic and personal protection measures against malaria exposure either divert host-seeking vectors to other hosts or kill those attempting to feed. Here, we explicitly model mosquito host-seeking processes [...] technology and distribution systems for insecticide-treated nets improve, massive reductions in malaria transmission could be realised
