Mosquito repellents for malaria prevention (Review) (Publications)
BACKGROUND: Malaria is an important cause of illness and death across endemic regions. Considerable success against malaria has been achieved within the past decade mainly through long-lasting insecti [...] alone. It is unclear if topical repellents can prevent clinical malaria (RR 0.65, 95% CI 0.4 to 1.07, very low certainty evidence) or malaria infection (RR 0.84, 95% CI 0.64 to 1.12, low-certainty evidence) [...] repellentsTwo cluster-randomized RCTs investigated mosquito coils for malaria...
Performance of antigen concentration thresholds for attributing fever to malaria among outpatients in Angola (Publications)
The density of malaria parasites is a key determinant in whether or not an infected individual develops fever. While the pyrogenic threshold for malaria parasite density has been well-studied, there is [...] latent-class modeling to attribute malaria etiology to the fevers and to estimate the sensitivity and specificity of different antigen thresholds for detecting malaria fevers. Amongst patients positive [...] febrile HRP2+ patients compared to afebrile HRP2+ patients. When considering HRP2...
Antagonistic effects of <em>Plasmodium</em>-helminth co-infections on malaria pathology in different population groups in Côte d'Ivoire (Publications)
INTRODUCTION: Plasmodium spp. and helminths are co-endemic in many parts of the tropics; hence, co-infection is a common phenomenon. Interactions between Plasmodium and helminth infections may alter t
Severe malaria and concomitant bacteraemia in children admitted to a rural Mozambican hospital (Publications)
severe malaria. RESULTS: Seven thousand and forty-three children were admitted with a diagnosis of malaria. 25.2% fulfilled the criteria for severe malaria. 5.4% of the children with severe malaria and valid [...] rates of severe malaria cases rose steeply when bacteraemia was also present (from 4.0% to 22.0%, P < 0.0001), and bacteraemia was an independent risk factor for death among severe malaria patients (adjusted [...] associated with severe malaria syndromes, or anaemia severity groups. No...