Human unconventional T cells in <em>Plasmodium falciparum</em> infection (Publications)
field of malaria immunology. Significant advances in our basic understanding of unconventional T cell biology in rodent malaria models have been made, however, their roles in humans during malaria are less [...] tissues, and long-lasting expansions and functional alterations were observed upon malaria infection in malaria naïve and malaria pre-exposed volunteers. Here, we review the current understanding of involvement [...] Malaria is an old scourge of humankind and has a large negative impact...
A good night's sleep and the habit of net use: perceptions of risk and reasons for bed net use in Bukoba and Zanzibar (Publications)
BACKGROUND: Intensive malaria control interventions in the United Republic of Tanzania have contributed to reductions in malaria prevalence. Given that malaria control remains reliant upon continued use [...] perceived risk of malaria had decreased among the respondents, and malaria control interventions were credited for the decline. Participants cited reductions in both the severity of malaria and in their perceived [...] perceived susceptibility to malaria. However, malaria was still...
A good night's sleep and the habit of net use: perceptions of risk and reasons for bed net use in Bukoba and Zanzibar (Publications)
BACKGROUND: Intensive malaria control interventions in the United Republic of Tanzania have contributed to reductions in malaria prevalence. Given that malaria control remains reliant upon continued use [...] perceived risk of malaria had decreased among the respondents, and malaria control interventions were credited for the decline. Participants cited reductions in both the severity of malaria and in their perceived [...] perceived susceptibility to malaria. However, malaria was still...
Analytics and Intervention Modelling (Page)
https://www.swisstph.ch/en/about/eph/health-interventions/analytics-and-intervention-modelling
Foundation President's Malaria Initiative Malaria Consortium Links & Downloads openMalaria r-openMalariaUtilities Emilie Pothin: "Modeling the impact of community health workers on malaria elimination" MOSASWA [...] more OpenMalaria Workflow and OpenMalariaUtilities R Packages The work of the Analytics and Intervention Modelling Group is based on OpenMalaria : an open-source C++ program for simulating malaria epidemiology [...] use OpenMalaria for applied country-specific scenario simulations....
Surveillance and Health Systems (Page)
https://www.swisstph.ch/en/topics/malaria/surveillance-and-health-systems
Surveillance and Health Systems for Malaria Recording when and where malaria occurs is essential for assessing disease trends and planning interventions. Where malaria is epidemic, a system that combines [...] health systems around the world. Malaria Antimalarial Drug Development Malaria Elimination Mosquito Biology and Control Project Highlights Improving Access to Malaria Care and Services for Children Under [...] Health supports Cameroon's National Malaria Control Programme in achieving...
Antigens released at schizont burst stimulate <em>Plasmodium falciparum</em>-specific CD4+ T cells from non-exposed donors: potential for... (Publications)
individuals can be stimulated by malaria parasites. Here, we show that nine from 11 blood samples, naturally infected with malaria parasites, could stimulate proliferation of a malaria-specific T cell clone derived [...] the T cell response of naive donors to malaria parasites, processing of parasite antigens is blocked by chloroquine and monensin, and activation of 36 of 41 malaria-specific clones tested was restricted [...] activation of cross-reactive memory T cells by malaria parasites...
Antigens released at schizont burst stimulate <em>Plasmodium falciparum</em>-specific CD4+ T cells from non-exposed donors: potential for... (Publications)
individuals can be stimulated by malaria parasites. Here, we show that nine from 11 blood samples, naturally infected with malaria parasites, could stimulate proliferation of a malaria-specific T cell clone derived [...] the T cell response of naive donors to malaria parasites, processing of parasite antigens is blocked by chloroquine and monensin, and activation of 36 of 41 malaria-specific clones tested was restricted [...] activation of cross-reactive memory T cells by malaria parasites...
Antimalarial Drug Development (Page)
https://www.swisstph.ch/en/topics/malaria/antimalarial-drug-development
endemic countries of tropical Africa. Malaria Basic Malaria Research Malaria Vaccines Project Highlights Drug Discovery for Malaria The NGBS programme in malaria drug discovery is a collaboration between [...] part of the Medicines for Malaria Venture portfolio. Link to Project Shaping Next-Generation Interventions for Malaria Prevention Despite progress to reduce malaria burden, malaria parasites are becoming [...] Treating malaria is a global challenge. Resistance against artemisinin-based...
Effects of age, gender and soil-transmitted helminth infection on prevalence of <em>Plasmodium </em>infection among population living in Bata... (Publications)
bed nets. Malaria infections were detected in 34.8% of the participants, while 50% of malaria infections were reported in children aged 10-17 years. Females had a lower prevalence of malaria (28.8%) compared [...] health impact of STH and malaria co-infection is inconclusive. The current study aimed to report the malaria and STH infection epidemiology in the continental region of Equatorial Guinea. METHODS: We performed [...] infected with T. trichiura had malaria parasites compared with those...
Effects of age, gender and soil-transmitted helminth infection on prevalence of <em>Plasmodium </em>infection among population living in Bata... (Publications)
bed nets. Malaria infections were detected in 34.8% of the participants, while 50% of malaria infections were reported in children aged 10-17 years. Females had a lower prevalence of malaria (28.8%) compared [...] health impact of STH and malaria co-infection is inconclusive. The current study aimed to report the malaria and STH infection epidemiology in the continental region of Equatorial Guinea. METHODS: We performed [...] infected with T. trichiura had malaria parasites compared with those...