Geo-epidemiology of malaria incidence in the Vhembe District to guide targeted elimination strategies, South-Africa, 2015-2018: a local resurgence (Publications)
to classify the 474 smoothed malaria incidence curves. Thereafter, validity indices were used to determine the number of malaria incidence patterns. The cumulative malaria incidence of the study area was [...] Findings show also unusual malaria phenomena in Vhembe District that hinder malaria elimination in South Africa. Assessing the factors associated with these unusual malaria phenome would be helpful on [...] results. Therefore, in the process of refining local malaria control and...
Occupational exposure to malaria, leishmaniasis and arbovirus vectors in endemic regions: a systematic review (Publications)
Vector-borne diseases, including dengue, leishmaniasis and malaria, may be more common among individuals whose occupations or behaviours bring them into frequent contact with these disease vectors outside [...] 16 online databases. The primary outcome was incidence or prevalence of dengue, leishmaniasis or malaria. The review excluded ecological and qualitative studies, abstracts only, letters, commentaries, reviews [...] Bite interventions for each risk group were assessed. 1170 articles were...
Severe coinfection of dengue and malaria: a case report (Publications)
substantial improvement in the diagnostic capacity. ABSTRACT: Here we report a case of dengue and malaria coinfection from the southeast region of Sudan, bordering Ethiopia and Eritrea. A 25-year-old male [...] vomiting, and muscle and joint pain. Laboratory investigations confirmed a coinfection of dengue and malaria, which is assumingly not uncommon in areas heavily syndemic with several diseases but it is severely [...] The case has fully recovered after the supportive care for dengue and...
Combined use of long-lasting insecticidal nets and <em>Bacillus thuringiensis israelensis</em> larviciding, a promising integrated approach against... (Publications)
BACKGROUND: The recent reduction in malaria burden in Côte d'Ivoire is largely attributable to the use of long-lasting insecticidal nets (LLINs). However, this progress is threatened by insecticide resistance [...] resistance and behavioral changes in Anopheles gambiae sensu lato (s.l.) populations and residual malaria transmission, and complementary tools are required. Thus, this study aimed to assess the efficacy [...] determined using a polymerase chain reaction technique. Plasmodium...
Reagent-free detection of <em>Plasmodium falciparum</em> malaria infections in field-collected mosquitoes using mid-infrared spectroscopy and machine... (Publications)
Field-derived metrics are critical for effective control of malaria, particularly in sub-Saharan Africa where the disease kills over half a million people yearly. One key metric is entomological inoculation [...] detect Plasmodium falciparum sporozoites in wild-caught Anopheles funestus, a major Afro-tropical malaria vector, without requiring any laboratory reagents. We collected 7178 female An. funestus from rural [...] detect P. falciparum in field-collected mosquitoes, with potential for...
Climate change, malaria and neglected tropical diseases: a scoping review (Publications)
To explore the effects of climate change on malaria and 20 neglected tropical diseases (NTDs), and potential effect amelioration through mitigation and adaptation, we searched for papers published from [...] 1543 full-text papers were assessed. Of 511 papers meeting the inclusion criteria, 185 studied malaria, 181 dengue and chikungunya and 53 leishmaniasis; other NTDs were relatively understudied. Mitigation [...] (34%) and adaption strategies in 24 (5%). Amplitude and direction of effects of...
Severe outcomes of malaria in children under time-varying exposure (Publications)
Plasmodium falciparum severe malaria dataset to better understand the relationship between prevalence and incidence of malaria pediatric hospitalizations - a proxy of malaria severe outcomes- in East-Africa [...] In malaria epidemiology, interpolation frameworks based on available observations are critical for policy decisions and interpreting disease burden. Updating our understanding of the empirical evidence [...] dynamics, and subsequent protection patterns in children, substantially...
The beauty of disease modelling (Page)
https://www.swisstph.ch/en/impact-stories/the-beauty-of-disease-modelling
modelling for malaria vaccines? Similar to vaccines, we often ask questions about how we can can reduce the burden of disease. Many of the malaria models that were created to look at malaria vaccines have [...] modelling here is not just estimating the impact of the malaria vaccine or a single intervention but we can ask a whole range of questions about malaria disease dynamics, intervention packages and drug resistance [...] n packages for different national malaria control programmes....
“It is a privilege to be able to bring science to the bedside” (Page)
https://www.swisstph.ch/en/impact-stories/it-is-a-privilege-to-be-able-to-bring-science-to-the-bedside
test a drug for a neglected disease such as malaria, the trial can become more complex, because we have to go where the malaria patients are, i.e., to a malaria-endemic country such as the DRC. Such sites [...] very effective and affordable medicines for malaria? Yes, artemisinin-based combination therapies (ACTs) are still the standard of care for treating malaria and remain very effective. However, we are seeing [...] in the fight against malaria? What is unique about Swiss TPH is that we work...
