Development of amplicon deep sequencing markers and data analysis pipeline for genotyping multi-clonal malaria infections (Publications)
BACKGROUND: Amplicon deep sequencing permits sensitive detection of minority clones and improves discriminatory power for genotyping multi-clone Plasmodium falciparum infections. New amplicon sequenci
malERA: an updated research agenda for malaria elimination and eradication (Publications)
burden and eliminating malaria through the "Global Technical Strategy" and 21 countries are aiming to eliminate malaria by 2020. The commitment to achieve these targets should be celebrated. However, the [...] goals, sustain elimination, and free the world of malaria is greater than ever. Over 180 experts across multiple disciplines are engaged in the Malaria Eradication Research Agenda (malERA) Refresh process [...] solved. The result is a research and development agenda to accelerate malaria...
The ethics of health care delivery in a pediatric malaria vaccine trial: the perspectives of stakeholders from Ghana and Tanzania (Publications)
care to participants and communities of low-resource settings involved in a Phase II/III pediatric malaria vaccine trial (PMVT). We conducted 52 key informant interviews with major stakeholders of an int
Attacking the mosquito on multiple fronts: insights from the vector control optimization model (VCOM) for malaria elimination (Publications)
nets (ITNs) and indoor residual spraying (IRS) in reducing malaria transmission, it is unlikely these tools will be sufficient to eliminate malaria transmission on their own in many settings today. Fortunately [...] performed for the main three malaria vectors in sub-Saharan Africa, Anopheles gambiae s.s, An. arabiensis and An. funestus. We considered areas having low, moderate and high malaria transmission, corresponding [...] however, there is growing evidence and consensus that effective...
The complex relationship of exposure to new <em>Plasmodium</em> infections and incidence of clinical malaria in Papua New Guinea (Publications)
The molecular force of blood-stage infection (molFOB) is a quantitative surrogate metric for malaria transmission at population level and for exposure at individual level. Relationships between molFOB
Global investment targets for malaria control and elimination between 2016 and 2030 (Publications)
Background: Access to malaria control interventions falls short of universal health coverage. The Global Technical Strategy for malaria targets at least 90% reduction in case incidence and mortality rates [...] to reach these targets will be determined in part by investments in malaria. This study estimates the financing required for malaria control and elimination over the 2016-2030 period. Methods: A mathematical [...] coverage on burden and costs. The cost analysis took a public provider...