Multiplex assay for species identification and monitoring of insecticide resistance in <em>Anopheles punctulatus</em> group populations of Papua New... (Publications)
complex [eight cryptic species]) are principal vectors of malaria and filariasis in the Southwest Pacific. Given significant effort to reduce malaria and filariasis transmission through insecticide-treated
Etiology of anemia among infants, school-aged children, and young non-pregnant women in different settings of south-central Côte d'Ivoire (Publications)
samples were subjected to standardized quality-controlled methods. We found high prevalence of anemia, malaria, inflammation, and deficiencies of iron, riboflavin, and vitamin A but low prevalence and intensities [...] factor for anemia in non-pregnant women. Our findings call for interventions to protect infants from malaria, improved intake of dietary iron, and given the importance of anemia of inflammation in school-aged
Systematic review of indoor residual spray efficacy and effectiveness against <em>Plasmodium falciparum</em> in Africa (Publications)
Indoor residual spraying (IRS) is an important part of malaria control. There is a growing list of insecticide classes; pyrethroids remain the principal insecticide used in bednets but recently, novel [...] of different IRS insecticides. We report that long-lasting IRS formulations substantially reduce malaria, though their benefit over cheaper, shorter-lived formulations depends on local factors including
COVID-19: Have we learned anything from previous lessons? (Page)
https://www.swisstph.ch/en/impact-stories/covid-19-have-we-learned-anything-from-previous-lessons
SARS-CoV-2, but the increase in malaria transmission now observed in many African countries is closely linked to the pandemic. The gains made over the past two decades in malaria control are now at risk. Linking [...] diseases, especially in remote areas, went untreated. It is estimated that 500,000 more people died of malaria and pneumonia during the Ebola epidemic than on average. This is known as "collateral damage." Worsening [...] overburdening fragile health systems: the negative effects...
The development of an ivermectin-based attractive toxic sugar bait (ATSB) to target <em>Anopheles arabiensis</em> (Publications)
Africa are moving towards malaria-elimination, mostly thanks to successful vector control campaigns. However, elimination has proven challenging, resulting in the persistence of malaria transmission. It is now [...] now accepted that in order to eliminate malaria, new complementary vector control approaches must be developed. This study describes the development of a sugar-baited resting place containing a toxic dose
Surveillance of molecular markers of <em>Plasmodium falciparum</em> artemisinin resistance (<em>kelch</em>13 mutations) in Papua New Guinea between... (Publications)
Plasmodium falciparum resistance to artemisinin-based combination therapy (ACT) is a global threat to malaria control and elimination efforts. Mutations in the P. falciparum kelch13 gene (Pfk13) that are associated [...] in other parts of PNG is unknown. We investigated the prevalence of Pfk13 mutations in multiple malaria-endemic regions of PNG. P. falciparum isolates (n = 1152) collected between 2016 and 2018 and assessed [...] Continued surveillance for molecular markers of drug resistance is...
Infection and co-infection with helminths and <em>Plasmodium</em> among school children in Côte d'Ivoire: results from a national cross-sectional... (Publications)
Helminth infection and malaria remain major causes of ill-health in the tropics and subtropics. There are several shared risk factors (e.g., poverty), and hence, helminth infection and malaria overlap geographically [...] provide a rationale to combine control interventions that simultaneously aim at helminthiases and malaria
Effects of changing mosquito host searching behaviour on the cost effectiveness of a mass distribution of long-lasting, insecticidal nets: a modelling... (Publications)
BACKGROUND: The effectiveness of long-lasting, insecticidal nets (LLINs) in preventing malaria is threatened by the changing biting behaviour of mosquitoes, from nocturnal and endophagic to crepuscular [...] stochastic simulation models, we studied the impact of a mass LLIN distribution on Plasmodium falciparum malaria. Specifically, we looked at impact in terms of episodes prevented during the effective life of the [...] occur within the same mosquito population. LLINs are likely cost effective...
Surveillance of molecular markers of <em>Plasmodium falciparum</em> artemisinin resistance (<em>kelch</em>13 mutations) in Papua New Guinea between... (Publications)
Plasmodium falciparum resistance to artemisinin-based combination therapy (ACT) is a global threat to malaria control and elimination efforts. Mutations in the P. falciparum kelch13 gene (Pfk13) that are associated [...] in other parts of PNG is unknown. We investigated the prevalence of Pfk13 mutations in multiple malaria-endemic regions of PNG. P. falciparum isolates (n = 1152) collected between 2016 and 2018 and assessed [...] Continued surveillance for molecular markers of drug resistance is...
Effects of changing mosquito host searching behaviour on the cost effectiveness of a mass distribution of long-lasting, insecticidal nets: a modelling... (Publications)
BACKGROUND: The effectiveness of long-lasting, insecticidal nets (LLINs) in preventing malaria is threatened by the changing biting behaviour of mosquitoes, from nocturnal and endophagic to crepuscular [...] stochastic simulation models, we studied the impact of a mass LLIN distribution on Plasmodium falciparum malaria. Specifically, we looked at impact in terms of episodes prevented during the effective life of the [...] occur within the same mosquito population. LLINs are likely cost effective...
