Jonathan L. Vennerstrom: I was standing on the shoulders of giants (Publications)
collaborations with the Swiss Tropical and Public Health Institute (Swiss TPH) and the Medicines for Malaria Venture (MMV) have paved the way for antimalarial and antischistosomal drugs. In recognition of his
Health Impact Assessment (HIA) | Services at Swiss TPH (Page)
https://www.swisstph.ch/en/services/health-impact-assessment
Read more Scoping study on gene drive use in malaria-transmitting mosquitoes in West Africa Genetically modified mosquitoes have great potential for malaria control. Together with the University of Liverpool [...] mosquito releases, raise awareness of genetic control tools for malaria among policy makers, and review regulatory frameworks for malaria control and genetically modified organisms in 15 West African countries [...] potential use of Anopheles mosquitoes containing a gene drive...
New 4-amino-2-azabicyclo[3.2.2]nonane derivatives and their antiprotozoal potencies (Publications)
East African sleeping sickness, Trypanosoma b. rhodesiense, and a protozoan parasite which causes Malaria tropica, Plasmodium falciparum K-1, a strain which is resistant to chloroquine and pyrimethamine
Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort (Publications)
s in early pregnancy. They are, therefore, not recommended by WHO as a first-line treatment for malaria in first trimester due to associated embryo-foetal toxicity in animal studies. The study assessed
New 4-amino-2-azabicyclo[3.2.2]nonane derivatives and their antiprotozoal potencies (Publications)
East African sleeping sickness, Trypanosoma b. rhodesiense, and a protozoan parasite which causes Malaria tropica, Plasmodium falciparum K-1, a strain which is resistant to chloroquine and pyrimethamine
Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort (Publications)
s in early pregnancy. They are, therefore, not recommended by WHO as a first-line treatment for malaria in first trimester due to associated embryo-foetal toxicity in animal studies. The study assessed
Medicine | Departments of Swiss TPH (Page)
https://www.swisstph.ch/en/about/med
TPH provides a dedicated emergency service for diagnosing malaria - even outside regular working hours - and diagnoses approximately 200 malaria and over 1,200 schistosomiasis cases per year. Managing and [...] countries of Africa, Asia and Eastern Europe. The majority of our clinical research addresses issues of malaria, HIV, tuberculosis, causes-of-fever studies, and the evaluation of treatments and vaccines or their [...] Children 15.12.2023 Milestone in the Fight Against Sleeping Sickness...
Long-lasting and fast-acting<em> in vivo</em> efficacious antiplasmodial azepanylcarbazole amino alcohol (Publications)
With approximately 429,000 deaths in 2016, malaria remains a major infectious disease where the need to treat the fever symptoms, but also to provide relevant post-treatment prophylaxis, is of major importance
Inhibitors of Plasmepsin II-potential antimalarial agents (Publications)
In order to overcome the problem of drug resistance in malaria, it appears wise to concentrate drug discovery efforts toward new structural classes and new mechanisms of action. We report our results,
Global Health at a Crossroads: Who Will Fill the Gap? (Blog)
https://www.swisstph.ch/en/impact-stories/global-health-at-a-crossroads-who-will-fill-the-gap/blog-id/102/blog-id/102
USAID funding freeze and shifting donor priorities are already disrupting essential programmes—from malaria elimination and HIV treatment to critical health system support. At Swiss TPH, we see the consequences
