Novel nucleoside-based antimalarial compounds (Publications)
The malaria-causing parasite Plasmodium falciparum employs a salvage pathway for the biosynthesis of nucleotides, in contrast to de novo biosynthesis that is utilized by the human host. A series of twenty-two
Impact Stories | Swiss TPH (Page)
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research. Read more 22.04.2021 Julia Richter, Swiss Malaria Group World Malaria Day 2021: In the shadows of the COVID-19 pandemic A world without malaria is within reach. At the same time, the COVID-19 pandemic [...] progress in the fight against malaria. This year's World Malaria Day on 25 April 2021 will draw attention to the fact that further efforts are needed to achieve the goal of a malaria-free world. Read more 21 [...] years, much has been invested in malaria prevention and treatment,...
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Mosquitoes on Behalf of Target Malaria ViALLIN MUsAcc - Visual Analysis of Long Lasting Insecticidal Nets to Maximise Universal Access Related Topics Infectious Diseases Malaria Human African Trypanosomiasis
Assessing the population coverage of a health demographic surveillance system using satellite imagery and crowd-sourcing (Publications)
in Malawi. The Majete Malaria Project Health and Demographic Surveillance System, in Malawi, started in 2014 to support a project with the aim of studying the reduction of malaria using an integrated control
Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery (Publications)
accelerate drug discovery for diseases of poverty, the Medicines for Malaria Venture (MMV) has released box sets of 400 compounds named the Malaria, Pathogen and Stasis Boxes. Here, we screened the Pathogen Box
Mapping of research on maternal health interventions in low- and middle-income countries: a review of 2292 publications between 2000 and 2012 (Publications)
systems strengthening, health promotion; and on five tracer conditions (haemorrhage, hypertension, malaria, HIV and other sexually transmitted infections (STIs)). Following review of 35,078 titles and abstracts [...] More than half the studies were done in sub-Saharan Africa (55.4 %), mostly addressing HIV and malaria. This region had low numbers of publications per hypertension and haemorrhage deaths, though South
Operational challenges to continuous LLIN distribution: a qualitative rapid assessment in four countries (Publications)
BACKGROUND: The World Health Organization recommends that long-lasting insecticidal nets (LLINs) for malaria prevention should be distributed continuously through antenatal care (ANC) and the expanded programme [...] participants were included (23 in Kenya, 13 in Malawi, 18 in Mali and 16 in Rwanda), drawn from malaria programmes, ANC and EPI programmes, government logistics units, and partner organizations. Interviews
Randomized, double-blind, placebo-controlled trial of oral artemether for the prevention of patent <em>Schistosoma haematobium </em>infections (Publications)
microhematuria and macrohematuria were assessed 3 weeks after the final dosing. We also monitored malaria parasitemia and treated positive cases with sulfadoxine-pyrimethamine (SP). Oral artemether was well [...] 0.001). Heavy S. haematobium infections, microhematuria and macrohematuria, and the incidence of malaria parasitemia were all significantly lower in artemether recipients. In conclusion, previous findings
Trends in weekly reported net use by children during and after rainy season in central Tanzania (Publications)
insecticidal nets (LLINs) is one of the principal interventions to prevent malaria in young children, reducing episodes of malaria by 50% and child deaths by one fifth. Prioritizing young children for net
Adherence to standard treatment guidelines among prescribers in primary healthcare facilities in the Dodoma region of Tanzania (Publications)
in 2872 cases. The nine most prevalent conditions were upper respiratory tract infections (25%), malaria (18%), diarrhoea (9.9%), pneumonia (6.1%), skin problems (5.8%), gastrointestinal diagnoses (5%) [...] of cases that did not adhere to STG was highest with patients with skin problems and lowest for malaria. Conclusion: Prescribers' general adherence to national STG in primary HCF in the public sector in