A 39-amino-acid C-terminal truncation of GDV1 disrupts sexual commitment in<em> Plasmodium falciparum</em> (Publications)
Malaria is a mosquito-borne disease caused by apicomplexan parasites of the genus Plasmodium. Completion of the parasite's life cycle depends on the transmission of sexual stages, the gametocytes, from [...] important to sustain GDV1 protein levels and thereby sexual commitment.IMPORTANCE Transmission of malaria-causing Plasmodium species by mosquitos requires the parasite to change from a continuously growing
Modified mosquito landing boxes dispensing transfluthrin provide effective protection against <em>Anopheles arabiensis</em> mosquitoes under simulated... (Publications)
BACKGROUND: Efforts to control malaria vectors have primarily focused on scaling-up of long-lasting insecticidal nets (LLINs) and indoor residual spraying. Although highly efficient against indoor-biting [...] outdoor-biting mosquitoes in the peri-domestic space. They have a potential role in combatting outdoor malaria transmission without interfering with effective indoor interventions such as LLINs
Modified mosquito landing boxes dispensing transfluthrin provide effective protection against <em>Anopheles arabiensis</em> mosquitoes under simulated... (Publications)
BACKGROUND: Efforts to control malaria vectors have primarily focused on scaling-up of long-lasting insecticidal nets (LLINs) and indoor residual spraying. Although highly efficient against indoor-biting [...] outdoor-biting mosquitoes in the peri-domestic space. They have a potential role in combatting outdoor malaria transmission without interfering with effective indoor interventions such as LLINs
Identification of oleamide in <em>Guatteria</em> recurvisepala by LC/MS-Based <em>Plasmodium falciparum</em> thioredoxin reductase ligand binding... (Publications)
current research on applications of mass spectrometry to natural product drug discovery against malaria aims to screen plant extracts for new ligands to PLASMODIUM FALCIPARUM thioredoxin reductase ( PFTrxR) [...] regulation of the parasite and is validated as a promising target for therapeutic intervention against malaria. In the present study, detannified methanol extracts from GUATTERIA RECURVISEPALA, LICANIA KALLUNKIAE
Attributes of <em>Anopheles gambiae</em> swarms in south central Uganda (Publications)
BACKGROUND: Anopheles gambiae continues to be widespread and an important malaria vector species complex in Uganda. New approaches to malaria vector control are being explored including population suppression
A 39-amino-acid C-terminal truncation of GDV1 disrupts sexual commitment in<em> Plasmodium falciparum</em> (Publications)
Malaria is a mosquito-borne disease caused by apicomplexan parasites of the genus Plasmodium. Completion of the parasite's life cycle depends on the transmission of sexual stages, the gametocytes, from [...] important to sustain GDV1 protein levels and thereby sexual commitment.IMPORTANCE Transmission of malaria-causing Plasmodium species by mosquitos requires the parasite to change from a continuously growing
Discovery and structure-activity relationships of pyrrolone antimalarials (Publications)
2000-fold) compared to a mammalian cell line (L6), and significant activity against a rodent model of malaria when administered intraperitoneally. Structure-activity relationship studies have indicated ways
New 2‑aminopyrimidine derivatives and their antitrypanosomal and antiplasmodial activities (Publications)
of sleeping sickness, Trypanosoma brucei rhodesiense, as well as against a causative organism of malaria, Plasmodium falciparum NF54. Their cytotoxic properties were determined with L-6 cells (rat skeletal
Discovery and structure-activity relationships of pyrrolone antimalarials (Publications)
2000-fold) compared to a mammalian cell line (L6), and significant activity against a rodent model of malaria when administered intraperitoneally. Structure-activity relationship studies have indicated ways
New 2‑aminopyrimidine derivatives and their antitrypanosomal and antiplasmodial activities (Publications)
of sleeping sickness, Trypanosoma brucei rhodesiense, as well as against a causative organism of malaria, Plasmodium falciparum NF54. Their cytotoxic properties were determined with L-6 cells (rat skeletal