Insecticide resistance and its association with target-site mutations in natural populations of <em>Anopheles gambiae</em> from eastern Uganda (Publications)
Insecticide resistance in Anopheles gambiae threatens the success of malaria vector control programmes in sub-Saharan Africa. In order to manage insecticide resistance successfully, it is essential to
The reliability of pre-travel history to decide on appropriate counseling and vaccinations: a prospective study (Publications)
history and the effect on advice regarding the administration of vaccines and recommendations for malaria prevention.METHODS: We included prospectively all consenting adults who had not planned an organized
Analysis of <em>Plasmodium falciparum</em> infections in a village community in Northern Nigeria: determination of msp2 genotypes and parasitespecific... (Publications)
PNG. The prevalence of IgG antibodies against the circumsporozoite protein (CSP), an indicator for malaria exposure, was over 85% in all age groups showing a high exposure of villagers to P. falciparum. OD
In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in <em>Plasmodium... (Publications)
artemisinin-based combination therapy (ACT) recommended as first-line treatment of Plasmodium falciparum malaria in disease-endemic countries. Studies by Eckstein-Ludwig and co-workers showed both thapsigargin
Global metabolic responses of NMRI mice to an experimental <em>Plasmodium berghei</em> infection (Publications)
metabolic profiling may provide a sensitive diagnostic tool of Plasmodium infection and the control of malaria more generally
Novel inhibitors of <em>Plasmodium falciparum</em> dihydroorotate dehydrogenase with anti-malarial activity in the mouse model (Publications)
Plasmodium falciparum, the causative agent of the most deadly form of human malaria, is unable to salvage pyrimidines and must rely on de novo biosynthesis for survival. Dihydroorotate dehydrogenase (DHODH)
Genomic distribution and functional characterisation of two distinct and conserved <em>Plasmodium falciparum</em> var gene 5' flanking sequences (Publications)
Approximately 50 highly diverse var genes distributed throughout the haploid genome of the malaria parasite Plasmodium falciparum code for PfEMP1 variants located on the surface of infected erythrocytes
Analysis of subtelomeric virulence gene families in <em>Plasmodium falciparum</em> by comparative transcriptional profiling (Publications)
have important implications for our understanding and future analyses of phenotypic variation in malaria parasites
Histopathological changes in adult <em>Schistosoma japonicum</em> harbored in mice treated with a single dose of mefloquine (Publications)
New research has shown that mefloquine, an arylaminoalcohol used against malaria, is active against Schistosoma japonicum and Schistosoma mansoni in vivo. To enhance our understanding of the potential
Schistosomiasis and soil-transmitted helminthiasis: common drugs for treatment and control (Publications)
More than 2 billion people are infected worldwide and the disease burden might approach that of malaria. Recognising the enormous public health significance of schistosomiasis and STH, particularly among
