Immunogenicity and protective efficacy of radiation-attenuated and chemo-attenuated PfSPZ vaccines in Equatoguinean adults (Publications)
chemoprophylaxis) have shown vaccine efficacies (VEs) of 100% against homologous controlled human malaria infection (CHMI) in nonimmune adults. Plasmodium falciparum sporozoite-CVac has never been assessed
Cloning of the repertoire of individual <em>Plasmodium falciparum</em> var genes using Transformation Associated Recombination (TAR) (Publications)
One of the major virulence factors of the malaria causing parasite is the Plasmodium falciparum encoded erythrocyte membrane protein 1 (PfEMP1). It is translocated to It the membrane of infected erythrocytes
Experience of safety monitoring in the context of a prospective observational study of artemether-lumefantrine in rural Tanzania: lessons learned for... (Publications)
l study for artemether-lumefantrine (AL) administered as first-line treatment for uncomplicated malaria in rural Tanzania. METHODS: Pharmacovigilance procedures were developed through collaboration between
FlexiChip package: an universal microarray with a dedicated analysis software for high-thoughput SNPs detection linked to anti-malarial drug... (Publications)
throughput analysis. The FlexiChip package is a promising tool for use in poor resource settings of malaria endemic countries
How much remains undetected? Probability of molecular detection of human <em>Plasmodia</em> in the field (Publications)
BACKGROUND: In malaria endemic areas, most people are simultaneously infected with different parasite clones. Detection of individual clones is hampered when their densities fluctuate around the detection
Identification of cryptic <em>Anopheles</em> mosquito species by molecular protein profiling (Publications)
Vector control is the mainstay of malaria control programmes. Successful vector control profoundly relies on accurate information on the target mosquito populations in order to choose the most appropriate
Surveillance-response systems: the key to elimination of tropical diseases (Publications)
systems for Asia Pacific and Africa with an initial focus on elimination of lymphatic filariasis, malaria and schistosomiasis; (ii) development of new strategies, tools and approaches, such as improved
Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and... (Publications)
of this latter scaffold could lead to the identification of new leads for the dual treatment of malaria and leishmaniasis
HPLC-based activity profiling for antiplasmodial compounds in the traditional Indonesian medicinal plant <em>Carica papaya</em> L (Publications)
decoctions of Carica papaya have been traditionally used in some parts of Indonesia to treat and prevent malaria. Leaf extracts and fraction have been previously shown to possess antiplasmodial activity in vitro
Defining health research for development: the perspective of stakeholders from an international health research partnership in Ghana and Tanzania (Publications)
GlaxoSmithKline (GSK, Vaccine Developer) and the global health nonprofit organisation PATH and its Malaria Vaccine Initiative program (PATH/MVI, Funder-Development Partner), (RTS, S) (NCT00866619). The r