Validation of <em>Plasmodium falciparum</em> dUTPase as the target of 5'-tritylated deoxyuridine analogues with anti-malarial activity (Publications)
BACKGROUND: Malaria remains as a major global problem, being one of the infectious diseases that engender highest mortality across the world. Due to the appearance of resistance and the lack of an effective
Climate Change (Page)
https://www.swisstph.ch/en/topics/environment-and-health/climate-change
2050, 6 billion people will be at risk of one or several of the ‘big 7’ climate-related diseases: malaria, haemorrhagic fevers, schistosomiasis, human African trypanosomiasis, Chagas disease, leishmaniasis [...] well as water related diseases. The second phase is focussig on the people's abilities to cope with malaria and bilharzia infections on the fringes of the Sahelian belt. Heavy rains and floods, associated
Screening open access compound libraries and repurposing drugs to identify and characterize new molecules active against schistosomiasis and other... (Publications)
Far from the baneful impact of the so-called “big three” (HIV/AIDS, tuberculosis and malaria), schistosomiasis and other worm infections, such as the soil-transmitted helminths (STH) for example, have [...] each, both compiled and provided by the non-profit product development partnership Medicines for Malaria Venture (MMV). One library, the Pathogen Box, was composed of drug-like molecules with already-known
Clinical Operations | A Trusted Partner in Clinical Trial Services (Page)
https://www.swisstph.ch/en/about/med/clinical-operations
a privilege to be able to bring science to the bedside” – Elisabeth Reus on the launch of a new malaria clinical trial in the DRC Our Team - 11 Nationalities, 150 Years of Combined Expertise We are a global [...] Dis . 2023;23(4):463-470. DOI: 10.1016/S1473-3099(22)00660-0 Related Topics Infectious Diseases Malaria Human African Trypanosomiasis (HAT) Tuberculosis Related Activities Clinical Trials Organisational
Screening open access compound libraries and repurposing drugs to identify and characterize new molecules active against schistosomiasis and other... (Publications)
Far from the baneful impact of the so-called “big three” (HIV/AIDS, tuberculosis and malaria), schistosomiasis and other worm infections, such as the soil-transmitted helminths (STH) for example, have [...] each, both compiled and provided by the non-profit product development partnership Medicines for Malaria Venture (MMV). One library, the Pathogen Box, was composed of drug-like molecules with already-known
Geography and health: role of human translocation and access to care (Publications)
human translocation and access to care" document enhanced disease transmission of diseases, such as malaria, leishmaniasis, schistosomiasis, COVID-19 (Severe acute respiratory syndrome corona 2) and Oropouche
Fine-scale spatial and temporal variations in insecticide resistance in <em>Culex pipiens</em> complex mosquitoes in rural south-eastern Tanzania (Publications)
Culex could negatively influence the acceptability of other interventions such as those used against malaria mosquitoes.
The antiprotozoal activity of sixteen asteraceae species native to Sudan and bioactivity-guided isolation of xanthanolides from <em>Xanthium... (Publications)
against T. CRUZI (Chagas disease), LEISHMANIA DONOVANI (Kala-Azar) as well as PLASMODIUM FALCIPARUM (Malaria tropica). Bioactivity-guided fractionation resulted in the isolation of four bioactive sesquiterpene
Monitoring <em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> using microsatellite markers indicates limited changes in population structure... (Publications)
transmission declines. Here we describe the first population genetic analysis of the major human malaria parasites, Plasmodium falciparum (Pf) and Plasmodium vivax (Pv) following nationwide distribution
Systematic review of the entomological impact of insecticide-treated nets evaluated using experimental hut trials in Africa (Publications)
Africa, diminishing the efficacy of insecticide-treated nets (ITNs) – the primary tool for preventing malaria. The entomological efficacy of indoor vector control interventions can be measured in experimental