Geo-epidemiology of malaria incidence in the Vhembe District to guide targeted elimination strategies, South-Africa, 2015-2018: a local resurgence (Publications)
to classify the 474 smoothed malaria incidence curves. Thereafter, validity indices were used to determine the number of malaria incidence patterns. The cumulative malaria incidence of the study area was [...] Findings show also unusual malaria phenomena in Vhembe District that hinder malaria elimination in South Africa. Assessing the factors associated with these unusual malaria phenome would be helpful on [...] results. Therefore, in the process of refining local malaria control and...
Variability in white blood cell count during uncomplicated malaria and implications for parasite density estimation: a WorldWide Antimalarial... (Publications)
count during acute uncomplicated malaria, and estimate the impact of using an assumed value of WBC on estimates of parasite density and clearance. METHODS: Uncomplicated malaria drug efficacy studies that measured [...] and vivax (n = 2678) malaria, respectively. At presentation, higher WBC counts were seen among patients with higher parasitaemia, severe anaemia and, for individuals with vivax malaria, in regions with shorter [...] reference. RESULTS: Eighty-four studies enrolling 27,656...
Hearing of malaria mosquitoes is modulated by a beta-adrenergic-like octopamine receptor which serves as insecticide target (Publications)
Malaria mosquitoes acoustically detect their mating partners within large swarms that form transiently at dusk. Indeed, male malaria mosquitoes preferably respond to female flight tones during swarm time
The malaria blood stage antigen <em>Pf</em>CyRPA formulated with the TLR-4 agonist adjuvant GLA-SE elicits parasite growth inhibitory antibodies in... (Publications)
BACKGROUND: Plasmodium falciparum cysteine-rich protective antigen (PfCyRPA) is an invasion complex protein essential for erythrocyte invasion. In contrast to several previously clinically tested mero
Malaria rapid diagnostic tests reliably detect asymptomatic <em>Plasmodium falciparum</em> infections in school-aged children that are infectious to... (Publications)
this study, malaria rapid diagnostic tests (mRDT), light microscopy (LM) and quantitative polymerase chain reaction (qPCR) were used to evaluate their performance detecting asymptomatic malaria infections [...] BACKGROUND: Asymptomatic malaria infections (Plasmodium falciparum) are common in school-aged children and represent a disease transmission reservoir as they are potentially infectious to mosquitoes. To [...] was 31.7% by qPCR, 18.2% by mRDT and 9.4% by LM. Approximately one-third (31.2%)...
Malaria elimination in Zanzibar: where next? (Publications)
progress made towards malaria elimination, effectiveness of the health systems in delivering malaria case management; and malaria financing. A desk review examined available malaria data, annual work plans [...] 2018, Zanzibar developed a national malaria strategic plan IV (2018-2023) to guide elimination of malaria by 2023. We assessed progress in the implementation of malaria activities as part of the end-term [...] with marked heterogeneity between areas. However, about 68% of the detected ma...
Species composition, infection rate and detection of resistant alleles in <em>Anopheles funestus</em> (Diptera: Culicidae) from Lare, a malaria... (Publications)
BACKGROUND: Anopheles funestus, which is considered as secondary vector of malaria in Ethiopia, is known to have several morphologically indistinguishable (sibling) species. Accurate identification of [...] wild type. None of the samples (Nā=ā169) were found positive for Plasmodium (P. falciparum/ovale/malariae/vivax) detection. CONCLUSION: All An. funestus s.l. samples from Lare were molecularly identified
Spatial prediction of malaria prevalence in Papua New Guinea: a comparison of Bayesian decision network and multivariate regression modelling... (Publications)
performance when developing malaria prevalence maps due to the multiple interacting factors that drive malaria prevalence in different geographical areas. When developing malaria prevalence maps, BDNs may [...] BACKGROUND: Considerable progress towards controlling malaria has been made in Papua New Guinea through the national malaria control programme's free distribution of long-lasting insecticidal nets, improved [...] linear model, GLM) in terms of malaria spatial risk prediction accuracy....
Mapping the endemicity and seasonality of clinical malaria for intervention targeting in Haiti using routine case data (Publications)
Towards the goal of malaria elimination on Hispaniola, the National Malaria Control Program of Haiti and its international partner organisations are conducting a campaign of interventions targeted to high-risk