Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate (Publications)
Fascioliasis is a zoonotic disease of considerable public health and great veterinary significance and new drugs are needed. OZ78 is a promising fasciocidal drug candidate. In order to support the dev
Neurophysiological evidence for muscle tone reduction by intrathecal baclofen at the brainstem level (Publications)
OBJECTIVE: Intrathecal baclofen (ITB) is an efficient treatment modality for severe spasticity that is considered to act at the spinal level. Its influence on phasic spasticity is usually determined c
The German view: effects of nitrogen dioxide on human health--derivation of health-related short-term and long-term values (Publications)
The presented overview concerning health relevant effects caused by nitrogen dioxide (NO2) resumes the current state of results from animal experiments and human studies (epidemiology and short-term c
An attributable risk model for exposures assumed to cause both chronic disease and its exacerbations (Publications)
BACKGROUND: Many chronic diseases are the product of an underlying pathologic condition and superimposed acute exacerbations. This model may apply to several conditions such as asthma, other obstructi