Outcome of delivery and cause-specific mortality and severe morbidity in early infancy: a Kenyan District Hospital birth cohort (Publications)
It has proven very difficult to determine the causes of early infant mortality and morbidity in Africa. We undertook a two-year, prospective birth cohort study in a rural Kenyan District Hospital to e
HIV-1 RNA levels in an African population-based cohort and their relation to CD4 lymphocyte counts and World Health Organization clinical staging (Publications)
Apart from a small number of reports from people who are based in hospitals, data on viral load in HIV-infected people in sub-Saharan Africa, where most infections occur, are lacking. We report serum
Relationship between HIV-1 Env subtypes A and D and disease progression in a rural Ugandan cohort (Publications)
OBJECTIVE: To investigate the role of HIV-1 envelope subtypes on disease progression in a rural cohort of Ugandan adults where two major HIV-1 subtypes (A and D) exist. METHODS: Participants of a clin
<em>Plasmodium falciparum</em> infections are associated with agglutinating antibodies to parasite-infected erythrocyte surface antigens among healthy... (Publications)
Antibodies to the highly diverse variant surface antigens (VSAs) expressed on Plasmodium falciparum-infected erythrocytes are thought to play a role in the development of naturally acquired immunity t
The effects of untreated bednets on malaria infection and morbidity on the Kenyan coast (Publications)
A study was conducted in order to determine whether children that slept under untreated bednets were protected against both malaria infection and clinical disease compared with children not sleeping u
<em>Plasmodium falciparum</em>-infected erythrocytes: agglutination by diverse Kenyan plasma is associated with severe disease and young host age (Publications)
The variant surface antigens (VSAs) of Plasmodium falciparum-infected red blood cells are potentially important targets of naturally acquired immunity to malaria. Natural infections induce agglutinati
Genetic diversity of <em>Plasmodium falciparum</em> parasites from Kenya is not affected by antifolate drug selection (Publications)
The genotypes of merozoite surface protein-1, merozoite surface protein-2 and glutamine rich protein are frequently used to distinguish recrudescence from reinfection when parasitaemia reappears after
Prognostic indicators of early and late death in children admitted to district hospital in Kenya: cohort study (Publications)
OBJECTIVES: To identify clinical indicators of immediate, early, and late mortality in children at admission to a sub-Saharan district hospital and to develop prognostic scores. DESIGN: Prospective co
