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1. Chemotherapy for major food-borne trematodes: a review (Publications)

   Chemotherapy for major food-borne trematodes: a review

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   Food-borne trematode infections, caused by liver flukes (Clonorchis, Fasciola, Opisthorchis), lung flukes (Paragonimus) and intestinal flukes (Echinostoma, Fasciolopsis, heterophyids), are significant

2. Using knowledge brokering to promote evidence-based policy-making: the need for support structures (Publications)

   Using knowledge brokering to promote evidence-based policy-making: the need for support structures

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3. Environmental determinants of atopic eczema phenotypes in relation to asthma and atopic sensitization (Publications)

   Environmental determinants of atopic eczema phenotypes in relation to asthma and atopic sensitization

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4. Triclabendazole and its two main metabolites lack activity against <em>Schistosoma mansoni</em> in the mouse model (Publications)

   Triclabendazole and its two main metabolites lack activity against <em>Schistosoma mansoni</em> in the mouse model

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5. Evaluation of quinolone derivatives for antitrypanosomal activity (Publications)

   Evaluation of quinolone derivatives for antitrypanosomal activity

   Relevance:

   About 160 fluoroquinolones and derivatives were tested for antitrypanosomal activity in a drug sensitivity assay followed by fluorometric evaluation. The most active quinolone compounds had IC50 value

6. Discovery of dual function acridones as a new antimalarial chemotype (Publications)

   Discovery of dual function acridones as a new antimalarial chemotype

   Relevance:

   Preventing and delaying the emergence of drug resistance is an essential goal of antimalarial drug development. Monotherapy and highly mutable drug targets have each facilitated resistance, and both a

7. Artesunate and artemether are effective fasciolicides in the rat model and in vitro (Publications)

   Artesunate and artemether are effective fasciolicides in the rat model and in vitro

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8. Trypanocidal, leishmanicidal and cytotoxic effects of anthecotulide-type linear sesquiterpene lactones from Anthemis auriculata (Publications)

   Trypanocidal, leishmanicidal and cytotoxic effects of anthecotulide-type linear sesquiterpene lactones from Anthemis auriculata

   Relevance:

   Trypanosomiasis and leishmaniasis pose major public health threats for many countries, particularly those in sub-Saharan Africa and South America. In the present study, we evaluated the in vitro antip

9. <em>Fasciola hepatica</em>: tegumental alterations in adult flukes following in vitro and in vivo administration of artesunate and artemether (Publications)

   <em>Fasciola hepatica</em>: tegumental alterations in adult flukes following in vitro and in vivo administration of artesunate and artemether

   Relevance:

   The tegumental changes in adult Fasciola hepatica induced by artemether and artesunate were assessed utilizing scanning electron microscopy (SEM). F hepatica were incubated with artemether and artesun

10. Antitrypanosomal activity of Phosphonylmethoxyalkylpurines (Publications)

    Antitrypanosomal activity of Phosphonylmethoxyalkylpurines

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