On the origin of <em>Mycobacterium ulcerans</em>, the causative agent of Buruli ulcer (Publications)
ABSTRACT: BACKGROUND: Mycobacterium ulcerans is an unusual bacterial pathogen with elusive origins. While closelyrelated to the aquatic dwelling M. marinum, M. ulcerans has evolved the ability to prod
Time to move from presumptive malaria treatment to laboratory-confirmed diagnosis and treatment in African children with fever (Publications)
BACKGROUND TO THE DEBATE: Current guidelines recommend that all fever episodes in African children be treated presumptively with antimalarial drugs. But declining malarial transmission in parts of sub
Eukaryotic translation elongation factor 1A (eEF1A) domain I from <em>S. cerevisiae</em> is required but not sufficient for inter-species... (Publications)
Ethanolamine phosphoglycerol (EPG) is a protein modification attached exclusively to eukaryotic elongation factor 1A (eEF1A). In mammals and plants, EPG is linked to conserved glutamate residues locat
A simulation model of African Anopheles ecology and population dynamics for the analysis of malaria transmission (Publications)
BACKGROUND: Malaria is one of the oldest and deadliest infectious diseases in humans. Many mathematical models of malaria have been developed during the past century, and applied to potential interven
Factors associated with compliance among users of solar water disinfection in rural Bolivia (Publications)
ABSTRACT: BACKGROUND: Diarrhoea is the second leading cause of childhood mortality, with an estimated 1.3 million deaths per year. Promotion of Solar Water Disinfection (SODIS) has been suggested as a