Preventing childhood malaria in Africa by protecting adults from mosquitoes with insecticide-treated nets (Publications)
BACKGROUND: Malaria prevention in Africa merits particular attention as the world strives toward a better life for the poorest. Insecticide-treated nets (ITNs) represent a practical means to prevent m
The use of insecticide-treated nets for reducing malaria morbidity among children aged 6-59 months, in an area of high malaria transmission in central... (Publications)
ABSTRACT: BACKGROUND: Long-lasting insecticidal nets (LLINs) are an important tool for controlling malaria. Much attention has been devoted to determine both the effect of LLINs on the reduction of Pl
Solar drinking water disinfection (SODIS) to reduce childhood diarrhoea in rural Bolivia: a cluster-randomized, controlled trial (Publications)
BACKGROUND: Solar drinking water disinfection (SODIS) is a low-cost, point-of-use water purification method that has been disseminated globally. Laboratory studies suggest that SODIS is highly efficac
Spatial risk profiling of <em>Plasmodium falciparum</em> parasitaemia in a high endemicity area in Côte d'Ivoire (Publications)
BACKGROUND: The objective of this study was to identify demographic, environmental and socioeconomic risk factors and spatial patterns of Plasmodium falciparum parasitaemia in a high endemicity area o
Differential patterns of infection and disease with <em>P. falciparum</em> and <em>P. vivax</em> in young Papua New Guinean children (Publications)
BACKGROUND: Where P. vivax and P. falciparum occur in the same population, the peak burden of P. vivax infection and illness is often concentrated in younger age groups. Experiences from malaria thera
Limited antigenic diversity of <em>Plasmodium falciparum</em> apical membrane antigen 1 supports the development of effective multi-allele vaccines (Publications)
BackgroundPolymorphism in antigens is a common mechanism for immune evasion used by many important pathogens, and presents major challenges in vaccine development. In malaria, many key immune targets
Simple fecal flotation is a superior alternative to guadruple kato katz smear examination for the detection of hookworm eggs in human stool (Publications)
BACKGROUND: Microscopy-based identification of eggs in stool offers simple, reliable and economical options for assessing the prevalence and intensity of hookworm infections, and for monitoring the su
Identification of the <em>Mycobacterium ulcerans</em> protein MUL_3720 as a promising target for the development of a diagnostic test for Buruli ulcer (Publications)
Buruli ulcer (BU) caused by Mycobacterium ulcerans is a devastating skin disease, occurring mainly in remote West African communities with poor access to health care. Early case detection and subseque