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1. A novel pyrazolopyridine with<em> in vivo</em> activity in <em>Plasmodium berghei</em>- and <em>Plasmodium falciparum</em>-infected mouse models from... (Publications)

   A novel pyrazolopyridine with<em> in vivo</em> activity in <em>Plasmodium berghei</em>- and <em>Plasmodium falciparum</em>-infected mouse models from structure-activity relationship studies around the core of recently identified antimalarial imidazopyrida

   Relevance:

   Toward improving pharmacokinetics, in vivo efficacy, and selectivity over hERG, structure-activity relationship studies around the central core of antimalarial imidazopyridazines were conducted. This

2. Preparation of antimalarial endoperoxides by a formal [2 + 2 + 2] cycloaddition (Publications)

   Preparation of antimalarial endoperoxides by a formal [2 + 2 + 2] cycloaddition

   Relevance:

   A formal [2 + 2 + 2] cycloaddition reaction between a 1,3-dione, an olefin, and molecular oxygen mediated by light is reported, which delivers endoperoxides in good yield through the formation of two

3. Childhood cancer and residential exposure to highways: a nationwide cohort study (Publications)

   Childhood cancer and residential exposure to highways: a nationwide cohort study

   Relevance:

   Children living near highways are exposed to higher concentrations of traffic-related carcinogenic pollutants. Several studies reported an increased risk of childhood cancer associated with traffic ex

4. Is <em>Caenorhabditis elegans</em> the magic bullet for anthelminthic drug discovery? (Publications)

   Is <em>Caenorhabditis elegans</em> the magic bullet for anthelminthic drug discovery?

   Relevance:

   Recent advances in handling and readout have facilitated high-throughput screens with Caenorhabditis elegans. A new study demonstrates that C. elegans is a useful tool in high-throughput anthelminthic

5. A novel isothermal microcalorimetry tool to assess drug effects on<em> Ancylostoma ceylanicum</em> and <em>Necator americanus</em> (Publications)

   A novel isothermal microcalorimetry tool to assess drug effects on<em> Ancylostoma ceylanicum</em> and <em>Necator americanus</em>

   Relevance:

   Soil-transmitted helminths, which affect the poorest communities, worldwide cause a range of symptoms and morbidity, yet few treatment options are available and drug resistance is a concern. To improv

6. Development and transferability of a nitrogen dioxide land use regression model within the Veneto region of Italy (Publications)

   Development and transferability of a nitrogen dioxide land use regression model within the Veneto region of Italy

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7. How do clinicians prefer cultural competence training? Findings from the DSM-5 cultural formulation interview field trial (Publications)

   How do clinicians prefer cultural competence training? Findings from the DSM-5 cultural formulation interview field trial

   Relevance:

   OBJECTIVE: This study's objective is to analyze training methods clinicians reported as most and least helpful during the DSM-5 Cultural Formulation Interview field trial, reasons why, and association

8. Will Ebola change the game? Ten essential reforms before the next pandemic. The report of the Harvard-LSHTM Independent Panel on the Global Response... (Publications)

   Will Ebola change the game? Ten essential reforms before the next pandemic. The report of the Harvard-LSHTM Independent Panel on the Global Response to Ebola

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9. Antiprotozoal selectivity of diimidazoline <em>N</em>-phenylbenzamides (Publications)

   Antiprotozoal selectivity of diimidazoline <em>N</em>-phenylbenzamides

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10. Highly antiplasmodial non-natural oxidative products of dioncophylline A: synthesis, absolute configuration, and conformational stability (Publications)

    Highly antiplasmodial non-natural oxidative products of dioncophylline A: synthesis, absolute configuration, and conformational stability

    Relevance:

    Four new compounds, the monomeric dioncotetralones A (6 a) and B (6 b) and the dimeric compounds jozimine A3 (7) and jozimine A4 (9), were semi-synthesized from the natural product dioncophylline A (4