Novel <em>in vivo</em> active anti-malarials based on a hydroxy-ethyl-amine scaffold (Publications)
A novel series of anti-malarials, based on a hydroxy-ethyl-amine scaffold, initially identified as peptidomimetic protease inhibitors is described. Combination of the hydroxy-ethyl-amine anti-malarial
Whole-genome sequencing of rifampicin-resistant <em>Mycobacterium tuberculosis</em> strains identifies compensatory mutations in RNA polymerase genes (Publications)
Epidemics of drug-resistant bacteria emerge worldwide, even as resistant strains frequently have reduced fitness compared to their drug-susceptible counterparts. Data from model systems suggest that t
Growth of mature beech in relation to ozone and nitrogen deposition: an epidemiological approach (Publications)
Stem increment of mature Fagus sylvatica L. from 57 plots in Switzerland was analysed with respect to environmental factors using multilinear regression. Nitrogen (N) deposition was positively correla
Phase change material for thermotherapy of Buruli ulcer: modelling as an aid to implementation (Publications)
A mathematical model was developed and validated to predict the thermal behaviour of a heat application device based on a phase change material (pcm) for the heat treatment of Mycobacterium ulcerans i
Country planning for health interventions under development: lessons from the malaria vaccine decision-making framework and implications for other new... (Publications)
Traditionally it has taken years or decades for new public health interventions targeting diseases found in developing countries to be accessible to those most in need. One reason for the delay has be