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1. Substituted 2-phenyl-imidazopyridines: a new class of drug leads for human African trypanosomiasis (Publications)

   Substituted 2-phenyl-imidazopyridines: a new class of drug leads for human African trypanosomiasis

   Relevance:

   A phenotypic screen of a compound library for antiparasitic activity on Trypanosoma brucei, the causative agent of human African trypanosomiasis, led to the identification of substituted 2-(3-aminophe

2. Use of B-type natriuretic peptide for the management of women with dyspnea (Publications)

   Use of B-type natriuretic peptide for the management of women with dyspnea

   Relevance:

   In studies with predominately male patients, B-type natriuretic peptide (BNP) levels have been shown to be helpful in the evaluation and management of patients who present with acute dyspnea. The effe

3. Activity of diimidazoline amides against <em>African trypanosomiasis</em> (Publications)

   Activity of diimidazoline amides against <em>African trypanosomiasis</em>

   Relevance:

   We identified several diimidazoline mono- and diamides that were as potent as pentamidine against Trypanosoma brucei rhodesiense in vitro. All of these were also less cytotoxic than pentamidine, but n

4. The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer) (Publications)

   The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer)

   Relevance:

   Praziquantel has been the mainstay of schistosomiasis control since 1984 and widely distributed since 2006 through 'preventive chemotherapy' programmes to school-aged children or at-risk populations.

5. Epistasis between antibiotic resistance mutations drives the evolution of extensively drug-resistant tuberculosis (Publications)

   Epistasis between antibiotic resistance mutations drives the evolution of extensively drug-resistant tuberculosis

   Relevance:

6. Anti-tick vaccines for the control of ticks affecting livestock (Publications)

   Anti-tick vaccines for the control of ticks affecting livestock

   Relevance:

7. Female predominance and transmission distortion in the long-QT syndrome (Publications)

   Female predominance and transmission distortion in the long-QT syndrome

   Relevance:

   BACKGROUND: Congenital long-QT syndrome is a disorder resulting in ventricular arrhythmias and sudden death. The most common forms of the long-QT syndrome, types 1 and 2, are caused by mutations in th

8. Effect of ibandronate on spontaneous osteonecrosis of the knee: a randomized, double-blind, placebo-controlled trial (Publications)

   Effect of ibandronate on spontaneous osteonecrosis of the knee: a randomized, double-blind, placebo-controlled trial

   Relevance:

   Based on this double-blind, placebo-controlled study, ibandronate has no beneficial effect on clinical and radiological outcome in patients with spontaneous osteonecrosis of the knee over and above an

9. Exposure of highway maintenance workers to fine particulate matter and noise (Publications)

   Exposure of highway maintenance workers to fine particulate matter and noise

   Relevance:

   In this study, we assessed the mixed exposure of highway maintenance workers to airborne particles, noise, and gaseous co-pollutants. The aim was to provide a better understanding of the workers' expo

10. Elemental composition of particulate matter and the association with lung function (Publications)

    Elemental composition of particulate matter and the association with lung function

    Relevance:

    BACKGROUND:: Negative effects of long-term exposure to particulate matter (PM) on lung function have been shown repeatedly. Spatial differences in the composition and toxicity of PM may explain differ