High collection efficiency electrostatic precipitator for in vitro cell exposure to concentrated ambient particulate matter (PM) (Publications)
A new sampling system, the in vitro electrostatic collector, was developed to collect ambient particles for in vitro studies. The system consists of two units: first, particles are concentrated by mea
European 1: a globally important clonal complex of <em>Mycobacterium bovis</em> (Publications)
We have identified a globally important clonal complex of Mycobacterium bovis by deletion analysis of over one thousand strains from over 30 countries. We initially show that over 99% of the strains o
Uses of mosquito-stage transmission-blocking vaccines against <em>Plasmodium falciparum</em> (Publications)
A quantitative framework is used to explore the potential applications and probable effects of sexual stage or mosquito stage transmission blocking vaccines (TBVs) against malaria. The combination of
Vaccines for enteric diseases: update on recent developments (Publications)
The 5th International Conference on Vaccines for Enteric Diseases (VED) attracted more than 250 delegates, mainly from industrialized countries. A total of 56 papers were presented and 46 posters were
Swiss registry for patients with cystic fibrosis: design, programming, implementation and first examples of use (Publications)
The Swiss Registry for Cystic Fibrosis (SRCF) was designed to collect demographic, clinical and therapeutic data from patients with cystic fibrosis (CF) in Switzerland. It was designed, programmed and
New 4-aminobicyclo[2.2.2]octane derivatives and their activities against <em>Plasmodium falciparum</em> and <em>Trypanosoma b. rhodesiense</em> (Publications)
A series of new 2-substituted 4-dialkylaminobicyclo[2.2.2]octane derivatives was prepared and the compounds were investigated for their activity against causative organisms of tropical diseases. The t
Synthesis of new esters and oximes with 4-aminobicyclo[2.2.2]octane structure and evaluation of their antitrypanosomal and antiplasmodial activities (Publications)
New 4-amino-6,7-diphenylbicyclo[2.2.2]octane derivatives, esters of bicyclo[2.2.2]octan-2-ols and O-methyl oximes of bicyclo[2.2.2]octan-2-ones were synthesised. Their activities against Trypanosoma b