Effect of irrigation and large dams on the burden of malaria on a global and regional scale (Publications)
Human-made ecologic transformations have occurred at an unprecedented rate over the past 50 years. Prominent among them are water resource development projects. An estimated 40,000 large dams and 800,
<em>Plasmodium berghei</em> ANKA: selection of resistance to piperaquine and lumefantrine in a mouse model (Publications)
We have selected piperaquine (PQ) and lumefantrine (LM) resistant Plasmodium berghei ANKA parasite lines in mice by drug pressure. Effective doses that reduce parasitaemia by 90% (ED(90)) of PQ and LM
The role of parasitic infections in atopic diseases in rural schoolchildren (Publications)
BACKGROUND: There is increasing evidence that the farming environment has a protective effect as regards allergic diseases. Exposure to animal parasites, particularly helminth infections, is common in
Comparative detection of trypanosomal DNA by loop mediated isotherma amplification and PCR from FTA cards spotted with patient blood (Publications)
We analyzed DNA eluted from FTA (Flinders Technology Associates) cards spotted with blood from Human African Trypanosomiasis (HAT) patients admitted at Lwala Hospital, Eastern Uganda, and Kaliua Healt
<em>Anopheles arabiensis</em> and <em>A. gambiae</em> chromosomal inversion polymorphism, feeding and resting behaviour in relation to insecticide... (Publications)
Differential responses of the mosquitoes Anopheles arabiensis and An. gambiae sensu stricto to house-spraying with DDT or lambda-cyhalothrin were evaluated in relation to chromosomal inversion polymor
Antileishmanial activity, cytotoxicity and QSAR analysis of synthetic dihydrobenzofuran lignans and related benzofurans (Publications)
A series of synthetic dihydrobenzofuran lignans and related benzofurans were evaluated for their cytotoxicity in a screening panel consisting of various human tumour cell lines, and for their antiprot
Development and validation of the Kilifi epilepsy beliefs and attitude scale (Publications)
Epilepsy remains misunderstood, particularly in resource poor countries (RPC). We developed and validated a tool to assess beliefs and attitudes about epilepsy among people with epilepsy (PWE) in Kili
A nucleoside transporter from <em>Trypanosoma brucei</em> involved in drug resistance (Publications)
Drug resistance of pathogens is an increasing problem whose underlying mechanisms are not fully understood. Cellular uptake of the major drugs against Trypanosoma brucei spp., the causative agents of