Boswellic acids show <em>in vitro</em> activity against <em>Leishmania donovani</em> (Publications)
In continuation of our search for leads from medicinal plants against protozoal pathogens, we detected antileishmanial activity in polar fractions of a dichloromethane extract from Boswellia serrata r
Antiprotozoal <em>Nor</em>-triterpene alkaloids from <em>Buxus sempervirens</em> L (Publications)
Malaria and human African trypanosomiasis (HAT; sleeping sickness) are life-threatening tropical diseases caused by protozoan parasites. Due to limited therapeutic options, there is a compelling need
Metabolic syndrome risk unexpectedly predicted by traditional food consumption: shifting food systems and health among the Awajun of the Peruvian... (Publications)
BACKGROUND: Dietary changes, especially declines in traditional food diversity and increases in the consumption of processed foods, have previously been shown to increase the risk of developing cardio
Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites: <em>Trichuris muris</em>,... (Publications)
Nine hundred million people are infected with the soil-transmitted helminths Ascaris lumbricoides (roundworm), hookworm, and Trichuris trichiura (whipworm). However, low single-dose cure rates of the
Pathogens that cause acute febrile illness among children and adolescents in Burkina Faso, Madagascar and Sudan (Publications)
BACKGROUND: The etiology and optimal clinical management of acute febrile illness (AFI) is poorly understood. METHODS: Blood samples taken from study participants with acute fever (> /=37.5 degrees C)
Quality control of long-lasting insecticidal nets: are we neglecting it? (Publications)
Over 2.2 billion long-lasting insecticidal nets (LLINs) for malaria control have been delivered to recipient countries. LLINs are the largest single item in the global malaria control budget. To be el
Dynamics of intestinal multidrug-resistant bacteria colonisation contracted by visitors to a high-endemic setting: a prospective, daily, real-time... (Publications)
Background: Antimicrobial resistance is highly prevalent in low-income and middle-income countries. International travel contributes substantially to the global spread of intestinal multidrug-resistan
Comparison of three in-house real PCR assays targeting kinetoplast DNA, the small subunit ribosomal RNA gene and the glucose-6-phosphate isomerase... (Publications)
To perform PCR from serum for the diagnosis of visceral leishmaniasis is convenient and much less invasive than the examination of deeper compartments such as bone marrow. We compared three Leishmania
