High failure rates of protease inhibitor-based antiretroviral treatment in rural Tanzania - a prospective cohort study (Publications)
BACKGROUND: Poor adherence to antiretroviral drugs and viral resistance are the main drivers of treatment failure in HIV-infected patients. In sub-Saharan Africa, avoidance of treatment failure on sec
Antimalarial <em>N</em>1,<em>N</em>3-dialkyldioxonaphthoimidazoliums: synthesis, biological activity, and structure-activity relationships (Publications)
Here we report the nanomolar potencies of N (1),N (3)-dialkyldioxonaphthoimidazoliums against asexual forms of sensitive and resistant Plasmodium falciparum. Activity was dependent on the presence of
Gambiense human African trypanosomiasis sequelae after treatment: a follow-up study 12 years after treatment (Publications)
The clinical presentation of Human African Trypanosomiasis (HAT) due to Trypanosoma brucei gambiense is well known, but knowledge on long-term sequelae is limited. In the frame of studies conducted be
High genomic diversity and heterogenous origins of pathogenic and antibiotic-resistan<em>t Escherichia coli </em>in household settings represent a... (Publications)
Escherichia coli is present in multiple hosts and environmental compartments as a normal inhabitant, temporary or persistent colonizer, and as a pathogen. Transmission of E. coli between hosts and wit
Correlates and outcomes of low physical activity posttransplant: a systematic review and meta-analysis (Publications)
BACKGROUND: Little is known about associations between low physical activity (PA) and its correlates and outcomes in solid organ transplant recipients. This systematic review with meta-analysis examin
The transferability of lipid loci across African, Asian and European cohorts (Publications)
Most genome-wide association studies are based on samples of European descent. We assess whether the genetic determinants of blood lipids, a major cardiovascular risk factor, are shared across populat
Evaluation of the fluorescence polarization assay as a rapid on-spot test for ruminant brucellosis in Côte d'Ivoire (Publications)
Brucellosis is a zoonosis of economic and public health concern. While most diagnostic tests for brucellosis can only be performed in the laboratory, the Fluorescence Polarization Assay (FPA) was deve