Cost of interventions to control schistosomiasis: a systematic review of the literature (Publications)
BACKGROUND: Schistosomiasis, a disease caused by blood flukes of the genus Schistosoma, belongs to the neglected tropical diseases. Left untreated, schistosomiasis can lead to severe health problems a
Mechanochemical formation of racemic praziquantel hemihydrate with improved biopharmaceutical properties (Publications)
Praziquantel (PZQ) is the first-line drug used against schistosomiasis, one of the most common parasitic diseases in the world. A series of crystalline structures including two new polymorphs of the p
Re-annotation of the <em>Theileria parva</em> genome refines 53% of the proteome and uncovers essential components of N-glycosylation, a conserved... (Publications)
BACKGROUND: The apicomplexan parasite Theileria parva causes a livestock disease called East coast fever (ECF), with millions of animals at risk in sub-Saharan East and Southern Africa, the geographic
Health and economic burden of respiratory syncytial virus (RSV) disease and the cost-effectiveness of potential interventions against RSV among... (Publications)
BACKGROUND: Respiratory syncytial virus (RSV) frequently causes acute lower respiratory infection in children under 5, representing a high burden in Gavi-eligible countries (mostly low-income and lowe
Total synthesis and antitrypanosomal activity of janadolide and simplified analogues (Publications)
Janadolide is a cyclic depsipeptide natural product isolated from the marine cyanobacterium Okeania sp. Herein, we describe the total synthesis of janadolide, along with eight simplified analogues, vi
Germline Elongator mutations in Sonic Hedgehog medulloblastoma (Publications)
Cancer genomics has revealed many genes and core molecular processes that contribute to human malignancies, but the genetic and molecular bases of many rare cancers remains unclear. Genetic predisposi
Aceitabilidade da quimioprofilaxia em área endêmica para a hanseníase: projeto PEP-Hans Brasil (Publications)
The aim was to analyze the acceptability of chemoprophylaxis with single-dose rifampicin (PEP) in contacts, index leprosy cases, and health professionals and related factors that can influence adheren
Association between the proportion of <em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> infections detected by passive surveillance and the... (Publications)
BACKGROUND: Passively collected malaria case data are the foundation for public health decision making. However, because of population-level immunity, infections might not always be sufficiently sympt
Early life risk factors of motor, cognitive and language development: a pooled analysis of studies from low/middle-income countries (Publications)
OBJECTIVE: To determine the magnitude of relationships of early life Ffactors with child development in low/middle-income countries (LMICs). DESIGN: Meta-analyses of standardised mean differences (SMD
