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1. Activity of artemether and mefloquine against juvenile and adult <em>Schistosoma mansoni</em> in athymic and immunocompetent NMRI mice (Publications)

   Activity of artemether and mefloquine against juvenile and adult <em>Schistosoma mansoni</em> in athymic and immunocompetent NMRI mice

   Relevance:

   Immune effector mechanisms can enhance the activity of antischistosomal drugs. We examined the in vivo effect of single oral doses of the antimalarials artemether (400 mg/kg) and mefloquine (200 mg/kg

2. Chemotherapy for major food-borne trematodes: a review (Publications)

   Chemotherapy for major food-borne trematodes: a review

   Relevance:

   Food-borne trematode infections, caused by liver flukes (Clonorchis, Fasciola, Opisthorchis), lung flukes (Paragonimus) and intestinal flukes (Echinostoma, Fasciolopsis, heterophyids), are significant

3. Using knowledge brokering to promote evidence-based policy-making: the need for support structures (Publications)

   Using knowledge brokering to promote evidence-based policy-making: the need for support structures

   Relevance:

4. Environmental determinants of atopic eczema phenotypes in relation to asthma and atopic sensitization (Publications)

   Environmental determinants of atopic eczema phenotypes in relation to asthma and atopic sensitization

   Relevance:

5. Triclabendazole and its two main metabolites lack activity against <em>Schistosoma mansoni</em> in the mouse model (Publications)

   Triclabendazole and its two main metabolites lack activity against <em>Schistosoma mansoni</em> in the mouse model

   Relevance:

6. Evaluation of quinolone derivatives for antitrypanosomal activity (Publications)

   Evaluation of quinolone derivatives for antitrypanosomal activity

   Relevance:

   About 160 fluoroquinolones and derivatives were tested for antitrypanosomal activity in a drug sensitivity assay followed by fluorometric evaluation. The most active quinolone compounds had IC50 value

7. Discovery of dual function acridones as a new antimalarial chemotype (Publications)

   Discovery of dual function acridones as a new antimalarial chemotype

   Relevance:

   Preventing and delaying the emergence of drug resistance is an essential goal of antimalarial drug development. Monotherapy and highly mutable drug targets have each facilitated resistance, and both a

8. Artesunate and artemether are effective fasciolicides in the rat model and in vitro (Publications)

   Artesunate and artemether are effective fasciolicides in the rat model and in vitro

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9. Trypanocidal, leishmanicidal and cytotoxic effects of anthecotulide-type linear sesquiterpene lactones from Anthemis auriculata (Publications)

   Trypanocidal, leishmanicidal and cytotoxic effects of anthecotulide-type linear sesquiterpene lactones from Anthemis auriculata

   Relevance:

   Trypanosomiasis and leishmaniasis pose major public health threats for many countries, particularly those in sub-Saharan Africa and South America. In the present study, we evaluated the in vitro antip

10. Liver morbidity due to <em>Schistosoma mekongi</em> in Cambodia after seven rounds of mass drug administration (Publications)

    Liver morbidity due to <em>Schistosoma mekongi</em> in Cambodia after seven rounds of mass drug administration

    Relevance:

    Severe liver disease due to Schistosoma mekongi was frequent in northern Cambodia. Between 1995 and 2002, seven rounds of mass chemotherapy (praziquantel) reduced infection from 50% to below 3%. In 20