Spirometer replacement and serial lung function measurements in population studies: results from the SAPALDIA study (Publications)
The Swiss Cohort Study on Air Pollution and Lung and Heart Disease in Adults (SAPALDIA), a population cohort study, used heated-wire spirometers in 1991 and 2002 and then ultrasonic spirometers in 201
Changes in IgE sensitization and total IgE levels over 20 years of follow-up (Publications)
BACKGROUND: Cross-sectional studies have reported a lower prevalence of sensitization in older adults, but few longitudinal studies have examined whether this is an aging or a year-of-birth cohort eff
Intermittency ratio: a metric reflecting short-term temporal variations of transportation noise exposure (Publications)
Most environmental epidemiology studies model health effects of noise by regressing on acoustic exposure metrics that are based on the concept of average energetic dose over longer time periods (i.e.
Common variants in Mendelian kidney disease genes and their association with renal function (Publications)
Many common genetic variants identified by genome-wide association studies for complex traits map to genes previously linked to rare inherited Mendelian disorders. A systematic analysis of common sing
Early detection of subjects at risk for vascular remodelling - results from the Swiss population-based study SAPALDIA (Publications)
QUESTIONS UNDER STUDY: As the burden of cardiovascular disease (CVD) increases globally, its prevention and risk assessment becomes ever more important. We thus investigated the longitudinal associati
Common genes underlying asthma and COPD? Genome-wide analysis on the Dutch hypothesis (Publications)
Asthma and chronic obstructive pulmonary disease (COPD) are thought to share a genetic background ("Dutch hypothesis"). We investigated whether asthma and COPD have common underlying genetic factors,