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1. Targeting a large active site: structure-based design of nanomolar inhibitors of <em>Trypanosoma brucei </em>trypanothione reductase (Publications)

   Targeting a large active site: structure-based design of nanomolar inhibitors of <em>Trypanosoma brucei </em>trypanothione reductase

   Relevance:

   Trypanothione reductase (TR) plays a key role in the unique redox metabolism of trypanosomatids, the causative agents of human African trypanosomiasis (HAT), Chagas' disease, and leishmaniases. Introd

2. Challenges and way forward (Publications)

   Challenges and way forward

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3. The HOSENG trial - effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on... (Publications)

   The HOSENG trial - effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on testing coverage: protocol of a cluster-randomized clinical trial in rural Lesotho

   Relevance:

   BACKGROUND: HIV-testing coverage remains below the targeted 90% despite efforts and resources invested. Home-based HIV-testing is a key approach endorsed by the World Health Organization (WHO), especi

4. Empfehlungen zur Malariaprophylaxe (Publications)

   Empfehlungen zur Malariaprophylaxe

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5. Ambient particulate air pollution and daily mortality in 652 cities (Publications)

   Ambient particulate air pollution and daily mortality in 652 cities

   Relevance:

   BACKGROUND: The systematic evaluation of the results of time-series studies of air pollution is challenged by differences in model specification and publication bias. METHODS: We evaluated the associa

6. VIBRA trial - effect of village-based refill of ART following home-based same-day ART initiation vs clinic-based ART refill on viral suppression among... (Publications)

   VIBRA trial - effect of village-based refill of ART following home-based same-day ART initiation vs clinic-based ART refill on viral suppression among individuals living with HIV: protocol of a cluster-randomized clinical trial in rural Lesotho

   Relevance:

   BACKGROUND: There is a need for evaluating community-based antiretroviral therapy (ART) delivery models to improve overall performance of HIV programs, specifically in populations that may have diffic

7. Needs and coordination mechanism for capacity building by the RNAS (Publications)

   Needs and coordination mechanism for capacity building by the RNAS

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8. Kritik an Population Attributable Fraction bei genauerem Hinsehen nicht gerechtfertigt (Publications)

   Kritik an Population Attributable Fraction bei genauerem Hinsehen nicht gerechtfertigt

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9. Determinants of health insurance enrolment in Ghana: evidence from three national household surveys (Publications)

   Determinants of health insurance enrolment in Ghana: evidence from three national household surveys

   Relevance:

   In 2003, Ghana implemented a National Health Insurance Scheme (NHIS) to move towards Universal Health Coverage. NHIS enrolment is mandatory for all Ghanaians, but the most recent estimates show that c

10. The impact of pastoralist mobility on tuberculosis control in Ethiopia: a systematic review and meta-synthesis (Publications)

    The impact of pastoralist mobility on tuberculosis control in Ethiopia: a systematic review and meta-synthesis

    Relevance:

    BACKGROUND: Directly observed treatment, short-course (DOTS) is the current mainstay to control tuberculosis (TB) worldwide. Context-specific adaptations of DOTS have impending implications in the fig