Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies (Publications)
INTRODUCTION: Novel cancer therapies are often approved with evidence from a single pivotal trial alone. There are concerns about the credibility of this evidence. Higher validity may be indicated by
RTS,S malaria vaccine pilot studies: addressing the human realities in large-scale clinical trials (Publications)
A malaria vaccine as part of the integrated malaria control and elimination efforts will have a major impact on public health in sub-Sahara Africa. The first malaria vaccine, RTS,S, now enters pilot i
Linking human behaviours and malaria vector biting risk in south-eastern Tanzania (Publications)
To accelerate malaria elimination in areas where core interventions such as insecticide-treated nets (ITNs) are already widely used, it is crucial to consider additional factors associated with persis
The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes (Publications)
The generation of protective humoral immunity after vaccination relies on the productive interaction between antigen-specific B cells and T follicular helper (Tfh) cells. Despite the central role of T
Detection of <em>Plasmodium falciparum</em> infected <em>Anopheles gambiae</em> using near‑infrared spectroscopy (Publications)
BACKGROUND: Large-scale surveillance of mosquito populations is crucial to assess the intensity of vector-borne disease transmission and the impact of control interventions. However, there is a lack o
Hitzeaktionspläne zur Prävention von hitzebedingten Todesfällen – Erfahrungen aus der Schweiz (Publications)
Since the record-breaking temperatures registered during summer 2003, cantonal health authorities in Switzerland have implemented measures to prevent adverse health effects from hot weather and heatwa
