Synthesis and <em>in vitro</em> testing of antimalarial activity of non-natural-type neocryptolepines: structure-activity relationship study of 2,11-... (Publications)
This report describes the synthesis and in vitro anti-malarial evaluations of certain C2 or C8 and C11-disubstituted 6-methyl-5H-indolo[2,3-b]quinoline (neocryptolepine congener) derivatives. To attai
Agreement between parents and adolescents on dental fluorosis: a population-based study (Publications)
This study evaluated the prevalence and severity of dental fluorosis and compared the reports from adolescents aged 12 to 18 years with those of their parents regarding the perceptions and concerns ar
Cinnamoylphenethyl amides from <em>Polygonum hyrcanicum</em> possess anti-trypanosomal activity (Publications)
A methanolic extract from aerial parts of Polygonum hyrcanicum (Polygonaceae) showed high activity against Trypanosoma brucei rhodesiense (IC50 = 3.7 microg/mL). Bioassay-guided fractionation of the e
The contribution of spatial analysis to understanding HIV/TB mortality in children: a structural equation modelling approach (Publications)
Background: South Africa accounts for more than a sixth of the global population of people infected with HIV and TB, ranking her highest in HIV/TB co-infection worldwide. Remote areas often bear the g
Performance of multi-cities land use regression models for nitrogen dioxide and fine particles (Publications)
BACKGROUND: Land use regression (LUR) models have mostly been developed to explain intra-urban variations in air pollution based on often small local monitoring campaigns. Transferability of LUR model
Effects of vector-control interventions on changes in risk of malaria parasiotaemia in sub-Saharan Africa: a spatial and temporal analysis (Publications)
BACKGROUND: In the past decade, decreases in clinical episodes and deaths due to malaria have been mainly associated with the expansion of vector-control measures, such as insecticide-treated bednets