Scoping Study for a Strategic Environmental Assessment (SEASS) on the potential operational use of gene drive in the main malaria-carrying Anopheles... (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/scoping-study-for-a-strategic-environmental-assessment-seass-on-the-potential-operational-use-of-gene-drive-in-the-main-malaria-carrying-anopheles-mosquito-species-in-west-africa-on-behalf-of-target-malaria
Target Malaria isa not-for-profit research consortium that aims to develop and share new, cost-effective, and sustainable genetic technologies to modify mosquitoes and reduce malaria transmission. The [...] The intervention which is currently in development by Target Malaria (i.e. a population suppression gene drive) works by reducing the ability of female mosquitoes to reproduce through non-mendelian inheritance [...] inheritance of an introduced gene targeting female fertility, thereby...
OpenMalaria Workflow and OpenMalariaUtilities R Packages (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/openmalaria-workflow-and-openmalariautilities-r-packages
Swiss TPH GitHub . OpenMalariaUtilities R Package At the core of our OpenMalaria Workflow is the OpenMalariaUtilities R package which is developed to allow the use of OpenMalaria directly from R. The package [...] OpenMalaria Workflow R Package The work of the Analytics and Intervention Modelling Group is based on OpenMalaria : an open-source C++ program for simulating malaria epidemiology and the impacts on that [...] TPH GitHub. The OpenMalaria Workflow R Package together with the OpenMalariaU...
Child Health and Infection with Low Density (CHILD) Malaria, a randomized controlled trial to assess the long-term health and socioeconomic impact of... (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/child-health-and-infection-with-low-density-child-malaria-a-randomized-controlled-trial-to-assess-the-long-term-health-and-socioeconomic-impact-of-interventions-targeting-low-density-malaria-infection-lmi-among-children-in-tanzania
As malaria transmission declines, an increasing proportion of infections persist in the body at low levels. Low-density malaria infection (LMI) are often chronic and represent a high proportion of infections [...] they may provide protective immunity again future malaria illness. There is a growing body evidence to suggest that LMI are associated with recurrent malaria, chronic anemia, poor growth, co-infection with [...] for malaria (using RDT and qPCR) three times annually, with AL...