Improvements in access to malaria treatment in Tanzania after switch to artemisinin combination therapy and the introduction of accredited drug... (Publications)
Dispensing Outlets (ADDO) was created in Tanzania. Tanzania changed its first-line treatment for malaria from sulphadoxine-pyrimethamine (SP) to artemether-lumefantrine (ALu) in 2007. Subsidized ALu was [...] made available in both health facilities and ADDOs. The effect of these interventions on access to malaria treatment was studied in rural Tanzania. METHODS: The study was carried out in the villages of Kilombero [...] outlets. The data were complemented with DSS population data. RESULTS:...
A simulation model of African Anopheles ecology and population dynamics for the analysis of malaria transmission (Publications)
BACKGROUND: Malaria is one of the oldest and deadliest infectious diseases in humans. Many mathematical models of malaria have been developed during the past century, and applied to potential interventions [...] However, malaria remains uncontrolled and is increasing in many areas, as are vector and parasite resistance to insecticides and drugs. METHODS: This study presents a simulation model of African malaria vectors
Models for short term malaria prediction in Sri Lanka (Publications)
time series of district malaria cases for their ability to predict the number of malaria cases one to four months ahead. The addition of covariates such as the number of malaria cases in neighbouring districts [...] monitored/diagnosed malaria cases allows for the study of forecasting models, with an aim to developing a forecasting system which could assist in the efficient allocation of resources for malaria control. METHODS: [...] BACKGROUND: Malaria in Sri Lanka is unstable and fluctuates in...
Social and cultural aspects of 'malaria' and its control in central Côte d'Ivoire (Publications)
behaviour is important for the effective control of malaria. The purpose of this study was to assess the knowledge, attitudes, practices and beliefs of 'malaria' and its control in two rural communities of central [...] employing a household asset-based approach. RESULTS: Malaria was identified as djekouadjo, the local folk name of the disease. Although people were aware of malaria-related symptoms and their association with [...] central Cote d'Ivoire, and to examine associations between 'mala...
Time to move from presumptive malaria treatment to laboratory-confirmed diagnosis and treatment in African children with fever (Publications)
declining malarial transmission in parts of sub-Saharan Africa, declining proportions of fevers due to malaria, and the availability of rapid diagnostic tests mean it may be time for this policy to change. This [...] to support a shift toward laboratory-confirmed rather than presumptive diagnosis and treatment of malaria in children under five
Artesunate-mefloquine combination therapy in acute <em>Plasmodium falciparum</em> malaria in young children: a field study regarding neurological and... (Publications)
BACKGROUND: Mefloquine-artesunate combination therapy for uncomplicated falciparum malaria is one of the treatments used in African children. Data concerning neurological safety in adults and children [...] study was conducted among African children between 10 and 20 kg with acute uncomplicated falciparum malaria. They were treated over three consecutive days with a paediatric fixed-dose combination of artesunate [...] RESULTS: From December 2007 to March 2009, 220 children with uncomplicated...
A tool box for operational mosquito larval control: preliminary results and early lessons from the Urban Malaria Control Programme in Dar es Salaam,... (Publications)
be protected from malaria by controlling aquatic stages of mosquitoes if cost-effective and scalable implementation systems can be designed. METHODS: A recently initiated Urban Malaria Control Programme [...] levels, respectively. One year of community-based larviciding reduced transmission by the primary malaria vector, Anopheles gambiae s.l., by 31% (95% C.I. = 21.6-37.6%; p = 0.04). CONCLUSION: This novel [...] novel management, monitoring and evaluation system for implementing routine...