Management of severe malaria cases learnings and challenges from the field (Publications)
A presentation on the management of severe malaria cases learnings and challenges from the field by Manuel Hetzel of the CARAMAL project.
Evaluating putative repellent 'push' and attractive 'pull' components for manipulating the odour orientation of host-seeking malaria vectors in the... (Publications)
BACKGROUND: Novel malaria vector control approaches aim to combine tools for maximum protection. This study aimed to evaluate novel and re-evaluate existing putative repellent 'push' and attractive 'pull' [...] 'pull' components for manipulating the odour orientation of malaria vectors in the peri-domestic space. METHODS: Anopheles arabiensis outdoor human landing catches and trap comparisons were implemented in [...] components led to a better understanding of their ability to affect...
Global Malaria Technical & Training Support Package, Phase 3 (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/global-malaria-technical-training-support-package-phase-3
global malaria control and elimination by shaping global and national malaria control and elimination policies, and ultimately to reduce the malaria burden and to increase the number of malaria-free zones [...] and national malaria strategies. Background Thanks to the scale-up of effective malaria vector control tools such as insecticide-treated mosquito nets, diagnostics and medicines, malaria mortality has [...] Back Malaria action plan, aligned with the 2016-2030 timeline of the Sustainable...
Nanotechnological immunoassay for rapid label-free analysis of candidate malaria vaccines (Publications)
Malaria is a life-threatening epidemic disease with half of the world's population at risk. Although its incidence rate has fallen since 2010, this ratio dramatically stalled between 2014 and 2018. New [...] molecules in serum samples. The immunoassay successfully diagnoses humoral immune responses induced by malaria vaccine candidates and reveals the timeline and stage of the infection. We applied the newly developed [...] antibody/vaccine solutions, to blood samples from clinical trials on...
Investigation of heterochromatin protein 1 function in the malaria parasite <em>Plasmodium falciparum</em> using a conditional domain deletion and... (Publications)
offers a tool for further studies on epigenetic regulation and life cycle decision in malaria parasites.IMPORTANCE Malaria is caused by unicellular Plasmodium species parasites that repeatedly invade and replicate [...] The human malaria parasite Plasmodium falciparum encodes a single ortholog of heterochromatin protein 1 (PfHP1) that plays a crucial role in the epigenetic regulation of various survival-related processes [...] domain and CSD of HP1 are functionally conserved between P....
Evaluation of the Papua New Guinea National Malaria Control Program, 2018-2020 (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/evaluation-of-the-papua-new-guinea-national-malaria-control-program-2018-2020
information on malaria control intervention coverage, prevalence of malaria infection, and on different aspects of the changing malaria epidemiology in PNG, including on the local transmission of malaria in the [...] distinct malaria burden amenable to different combinations of interventions) Activity 2: School Malaria Survey (assessing malaria prevalence in school aged schildren) Activity 3: National Malaria Indicator [...] considered the country with the highest malaria transmission outside of...
Modeling support for BMGF Malaria Portfolio Analysis (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/modeling-support-for-bmgf-malaria-portfolio-analysis
in the malaria product portfolio of the Bill & Melinda Gates Foundation and partners. This model-based evidence combined with costs and economic analysis supports strategic decisions for malaria.
Developing a modelling framework for malaria transmission prevention tools (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/developing-a-modelling-framework-for-malaria-transmission-prevention-tools
to target these new malaria interventions, become more important. B y using mathematical models, this project will provide evidence to understand determinants of transformative malaria tools that interrupt [...] Following years of investment in strategies to control malaria, elimination is now being considered. But optimal delivery strategies and profiles for new tools for elimination differ from those of disease [...] project will inform setting of Target Product Profiles for novel prevent...
Global Malaria Technical & Training Support Package - phase 2 (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/global-malaria-technical-training-support-package-phase-2
aims at influencing global malaria policies and implementing WHO and Roll Back Malaria Partnership strategies to regional and country levels, with a focus on vector control, malaria case management, promoting [...] g technical capacities. The aim is to improve malaria program’s performance at country level ultimately to reduce the malaria burden and to expand malaria-free zones according to global goals set by WHO