Malaria seasonality and rainfall seasonality in Sri Lanka are correlated in space (Publications)
seasonality of malaria and seasonality of rainfall was studied in Sri Lanka. A simple seasonality index was developed by making use of the bimodal seasonality of both malaria and rainfall. The malaria seasonality [...] rainfall seasonality index in explaining the malaria seasonality index was found to be significant. The results suggest that rainfall is an important driver of malaria seasonality
Mapping and predicting malaria transmission in the People's Republic of China, using integrated biology-driven and statistical models (Publications)
humidity, which thus determines the extent of malaria transmission. However, in regions with relative humidity > 60%, temperature is the major driver of malaria transmission intensity. By integrating bio [...] The purpose of this study was to deepen our understanding of Plasmodium vivax malaria transmission patterns in the People's Republic of China (P.R. China). An integrated modeling approach was employed [...] and statistical models. A Delphi approach was used to determine environmental...
Assessing the effects of malaria interventions on the geographical distribution of parasitaemia risk in Burkina Faso (Publications)
nationally representative household malaria survey in 2010/2011. The survey collected among others, information on malaria interventions, treatment choices and malaria parasite prevalence in children aged [...] residual spray (IRS), artemisinin-based combination therapy (ACT) coverage associated with childhood malaria parasite risk at national and sub-national level, after taking into account geographical disparities [...] where interventions are being effective. These outputs are valuable tools...
Operational strategies of anti-malarial drug campaigns for malaria elimination in Zambia's southern province: a simulation study (Publications)
strategies for parasite clearance in southern province. METHODS: OpenMalaria, a discrete-time, individual-based stochastic model of malaria, was parameterized for the study area to simulate anti-malarial drug [...] BACKGROUND: Malaria elimination requires reducing both the potential of mosquitoes to transmit parasites to humans and humans to transmit parasites to mosquitoes. To achieve this goal in Southern province
Policy analysis for deciding on a malaria vaccine RTS,S in Tanzania (Publications)
stakeholders in Tanzania to assess malaria treatment policy changes and to draw lessons for malaria vaccine adoption. RESULTS: The decision-making process for adopting malaria interventions and new vaccines [...] policy makers and stimulate the decision-making process. In the case of the proposed introduction of malaria vaccines in Tanzania, a specific framework for decision-making will speed up the administrative process [...] Promoting factors include; epidemiological and intervention...
Identification of new human malaria parasite <em>Plasmodium falciparum</em> dihydroorotate dehydrogenase inhibitors by pharmacophore and... (Publications)
Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH), a key enzyme in the de novo pyrimidine biosynthesis pathway, which the Plasmodium falciparum relies on exclusively for survival, has emerg
