Understanding heterogeneities in the epidemiology of malaria in Papua New Guinea (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/understanding-heterogeneities-in-the-epidemiology-of-malaria-in-papua-new-guinea
Background Malaria has been endemic across most parts of Papua New Guinea (PNG) at endemicity levels comparable to sub-Saharan Africa. The National Malaria Control Program (NMCP) has managed to substantially [...] impact of malaria control interventions and underlying secular trends. Drivers of change, and reasons for differences between sites will be investigated. 2) Geo-referenced data on clinical malaria cases will [...] ongoing mathematical modelling of heterogeneities in malaria dynamics at...
Estimating the extent, patterns and consequences of heterogeneity in malaria dynamics (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/estimating-the-extent-patterns-and-consequences-of-heterogeneity-in-malaria-dynamics
Background The uneven distribution of malaria is apparent on a small scale, within a single study site or even cluster of houses. Transmission varies with mosquito densities related to breeding sites, [...] relatively high transmission, have been identified. Heterogeneity has implications for many areas of malaria epidemiology, not least the design of intervention strategies. Whilst the existence of heterogeneity [...] heterogeneity, and inform the design of control strategies and the...
Movement rates of African malaria vectors and their implications in models of vector control interventions (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/movement-rates-of-african-malaria-vectors-and-their-implications-in-models-of-vector-control-interventions
Movement rates of African malaria vectors and their implications in models of vector control interventions.
Evaluation of the Papua New Guinea National Malaria Control Program, 2015-2017 (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/evaluation-of-the-papua-new-guinea-national-malaria-control-program-2015-2017
AIDS, Tuberculosis and Malaria for the implementation of its malaria control program for the period 2015-2017. A range of partners are involved in the implementation of malaria control interventions ( [...] Against Malaria (RAM) and Population Services International (PSI) . The Papua New Guinea Institute of Medical Research (PNGIMR) has provided outcome and impact evaluation for the National Malaria Control
Preclinical profiling of virosomally formulated B-cell epitope mimetics derived from the novel key malaria vaccine candidates CyRPA and RH5 (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/preclinical-profiling-of-virosomally-formulated-b-cell-epitope-mimetics-derived-from-the-novel-key-malaria-vaccine-candidates-cyrpa-and-rh5
Clinical testing of two components for a synthetic peptide-based virosomal malaria vaccine has yielded promising results, encouraging the search for additional components for inclusion in a final multivalent
Papua New Guinea National Malaria Control Programme Evaluation and Operational Research 2021 to 2023 (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/papua-new-guinea-national-malaria-control-programme-evaluation-and-operational-research-2021-to-2023
exhibits a complex malaria epidemiology with marked heterogeneity in malaria transmission. With financial support from the Global Fund to Fight AIDS, Tuberculosis and Malaria, the National Malaria Control Program [...] across PNG to assess quality of malaria case management. Activity 2: a national Malaria Indicator Survey (MIS) to track progress in malaria intervention coverage and malaria prevalence on national and regional [...] changing malaria epidemiology in PNG (including aspects related...
Impact of systems failures in malaria service delivery in Africa (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/impact-of-systems-failures-in-malaria-service-delivery-in-africa
evaluate effective coverage of malaria curative interventions in Sub-Saharan Africa. We quantify excess morbidity and mortality induced by sub-optimal distribution of malaria services incorporating, among [...] Malaria treatment provides individual benefits by curing infection and preventing progression to severe disease. Treatment also provides community-level benefits by reducing the infectious reservoir. However [...] ent and the extent of health benefits achieved by such care, thus has...
Understanding the human, parasite, vector and environmental interactions driving residual malaria transmission in Papua New Guinea (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/understanding-the-human-parasite-vector-and-environmental-interactions-driving-residual-malaria-transmission-in-papua-new-guinea
The scale-up of malaria control in Papua New Guinea (PNG) has resulted in a significant reduction in the nationwide prevalence and incidence of malaria. However, this effect has not been uniform across [...] address this knowledge gap by: measuring the prevalence and distribution of malaria infection to assess the magnitude of residual malaria at the time of study, studying the Anopheles vectors to characterize local [...] heterogeneity in malaria transmission and the its driving factors is...