Malaria rapid tests, febrile illness management, and child mortality across sub-Saharan African countries (Publications)
IMPORTANCE: A prompt malaria diagnosis is crucial for the management of children with febrile illness in sub-Saharan African countries, where malaria remains a leading cause of mortality among children [...] distribution of point-of-care rapid diagnostic tests (RDTs) for malaria has transformed practice, but limited systematic evidence exists on how malaria RDTs have affected the management of febrile illness and [...] deaths per 1000 child-years). The effects of malaria RDT distribution on...
Potential impact of climatic factors on malaria in Rwanda between 2012 and 2021: a time-series analysis (Publications)
change and malaria dynamics, which hinders the development of effective national malaria response strategies. Addressing this critical gap, this study analyses how climatic factors influence malaria transmission [...] BACKGROUND: Malaria remains an important public health problem, particularly in sub-Saharan Africa. In Rwanda, where malaria ranks among the leading causes of mortality and morbidity, disease transmission [...] temperature and cumulative rainfall on malaria incidence in Rwanda from...
Spatio-temporal dynamics of malaria in Rwanda between 2012 and 2022: a demography-specific analysis (Publications)
eventually interrupt malaria transmission, the disease remains a pressing public health problem, especially in sub-Saharan Africa. This study presents a detailed spatio-temporal analysis of malaria transmission [...] insights into the evolving patterns of malaria and to inform and tailor effective public health strategies. METHODS: The study used yearly aggregated data of malaria cases from the Rwanda health management [...] temporal patterns of relative risks and to identify clusters of malaria...
Occupational exposure to malaria, leishmaniasis and arbovirus vectors in endemic regions: a systematic review (Publications)
Vector-borne diseases, including dengue, leishmaniasis and malaria, may be more common among individuals whose occupations or behaviours bring them into frequent contact with these disease vectors outside [...] 16 online databases. The primary outcome was incidence or prevalence of dengue, leishmaniasis or malaria. The review excluded ecological and qualitative studies, abstracts only, letters, commentaries, reviews [...] Bite interventions for each risk group were assessed. 1170 articles were...
Severe coinfection of dengue and malaria: a case report (Publications)
substantial improvement in the diagnostic capacity. ABSTRACT: Here we report a case of dengue and malaria coinfection from the southeast region of Sudan, bordering Ethiopia and Eritrea. A 25-year-old male [...] vomiting, and muscle and joint pain. Laboratory investigations confirmed a coinfection of dengue and malaria, which is assumingly not uncommon in areas heavily syndemic with several diseases but it is severely [...] The case has fully recovered after the supportive care for dengue and...
Combined use of long-lasting insecticidal nets and <em>Bacillus thuringiensis israelensis</em> larviciding, a promising integrated approach against... (Publications)
BACKGROUND: The recent reduction in malaria burden in Côte d'Ivoire is largely attributable to the use of long-lasting insecticidal nets (LLINs). However, this progress is threatened by insecticide resistance [...] resistance and behavioral changes in Anopheles gambiae sensu lato (s.l.) populations and residual malaria transmission, and complementary tools are required. Thus, this study aimed to assess the efficacy [...] determined using a polymerase chain reaction technique. Plasmodium...
Reagent-free detection of <em>Plasmodium falciparum</em> malaria infections in field-collected mosquitoes using mid-infrared spectroscopy and machine... (Publications)
Field-derived metrics are critical for effective control of malaria, particularly in sub-Saharan Africa where the disease kills over half a million people yearly. One key metric is entomological inoculation [...] detect Plasmodium falciparum sporozoites in wild-caught Anopheles funestus, a major Afro-tropical malaria vector, without requiring any laboratory reagents. We collected 7178 female An. funestus from rural [...] detect P. falciparum in field-collected mosquitoes, with potential for...
The impact of soil transmitted helminth on malaria clinical presentation and treatment outcome: a case control study among children in Bagamoyo... (Publications)
been documented between Plasmodium and STH. This study investigated the impact of STH on clinical malaria presentation and treatment outcome. METHODS: A matched case control study with a semi longitudinal [...] areas of Bagamoyo, coastal region of Tanzania. Cases were children with uncomplicated and severe malaria enrolled from the health facilities while controls were children with asymptomatic Plasmodium parasitemia [...] regression analysis there was a tendency for a protective effect of STH...