A large <em>Plasmodium vivax</em> reservoir and little population structure in the South Pacific (Publications)
INTRODUCTION: The importance of Plasmodium vivax in malaria elimination is increasingly being recognized, yet little is known about its population size and population genetic structure in the South Pacific [...] Pacific, an area that is the focus of intensified malaria control. METHODS: We have genotyped 13 microsatellite markers in 295 P. vivax isolates from four geographically distinct sites in Papua New Guinea [...] in sharp contrast to results from regions of low P. vivax endemicity. Prior...
Health facility-based data on women receiving sulphadoxine-pyrimethamine during pregnancy in Tanzania: lessons to learn from a cross-sectional survey... (Publications)
data on women receiving sulphadoxine-pyrimethamine (SP) for intermittent preventive treatment of malaria during pregnancy (IPTp) was carried out at antenatal care clinics in Mkuranga and Mufindi districts [...] system (HMIS) registers, interviews with health-care workers (HWs) and district and national level malaria control program managers corroborated by inter-temporal assessment through observations at HF levels [...] measures are urgently needed to accommodate data on new interventions and...
Eastern Africa, Madagascar and Indian Ocean Islands (Publications)
Travellers in East Africa are potentially exposed to malaria, arboviral infections, schistosomiasis, African sleeping sickness (African trypanosomiasis) and many other infectious diseases. Exposure determines [...] presenting with an acute febrile illness may have acquired an infection specific to the region (e.g. malaria, African tick bite fever) or common worldwide (e.g. influenza, EBV). East Africa is the second most [...] of the region. Of concern are recent reports of emerging artemisinin...
Visual Analysis of Long Lasting Insecticidal Nets to Maximise Universal Access (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/visual-analysis-of-long-lasting-insecticidal-nets-to-maximise-universal-access
vital in reducing the malaria burden among children over the last 20 years. Reductions have stagnated and resources available for control are half what is needed to meet malaria control milestones. Standard [...] between products, influencing their value-for-money. This project will deliver information to National Malaria Control Programs (NMCP) that enables them to 1) select durable and cost-effective LLINs to buy, 2) [...] NMCP=medium to select the best LLINs for their setting to optimize the...
WHO TVC (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/who-tvc
Increasing coverage of malaria vector control interventions globally has led to significant reductions in disease burden. However due to its high recurrent cost, there is a need to determine if and when [...] reduced. We conduct literature reviews and simulate a mathematical model of Plasmodium falciparum malaria epidemiology to determine the impact of scaling back vector control on transmission and disease.
Discovery and structure-activity relationships of quinazolinone-2-carboxamide derivatives as novel orally efficacious antimalarials (Publications)
against laboratory-resistant strains of malaria. Profiling of 19f suggested a fast in vitro killing profile. In vivo activity in a murine model of human malaria in a dose-dependent manner constitutes a
Discovery and structure-activity relationships of quinazolinone-2-carboxamide derivatives as novel orally efficacious antimalarials (Publications)
against laboratory-resistant strains of malaria. Profiling of 19f suggested a fast in vitro killing profile. In vivo activity in a murine model of human malaria in a dose-dependent manner constitutes a
Dietary diversity in primary schoolchildren of south-central Côte d'Ivoire and risk factors for non-communicable diseases (Publications)
prediabetes and malaria infection, as well as medium and high DDS. Overweight was associated with malaria infection and moderate anaemia. CONCLUSION: Overweight, prediabetes, low HDL-C, malaria, and anaemia [...] the primary caretaker according to the guideline of Food and Agriculture Organization. Anaemia, malaria, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and blood [...] health in Taabo. Our findings highlight interactions between infectious...
Comparative efficacy of Vector Guard® to Olyset® Plus insecticide-treated nets against strongly pyrethroid-resistant <em>Anopheles arabiensis</em> in... (Publications)
promising pyrethroid–PBO ITN for the control of resistant malaria vectors. The addition of Vector Guard® to the class of pyrethroid–PBO ITNs will enable malaria control programs to select cost-effective ITNs, improving [...] Introduction: The resistance of malaria vectors to pyrethroids has compromised the efficacy of pyrethroid insecticide-treated nets (ITNs). In response, ITNs with pyrethroids and piperonyl butoxide (PBO) [...] conducted to evaluate Vector Guard® relative to Olyset® Plus (a...
Dietary diversity in primary schoolchildren of south-central Côte d'Ivoire and risk factors for non-communicable diseases (Publications)
prediabetes and malaria infection, as well as medium and high DDS. Overweight was associated with malaria infection and moderate anaemia. CONCLUSION: Overweight, prediabetes, low HDL-C, malaria, and anaemia [...] the primary caretaker according to the guideline of Food and Agriculture Organization. Anaemia, malaria, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and blood [...] health in Taabo. Our findings highlight interactions between infectious...
