Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort (Publications)
s in early pregnancy. They are, therefore, not recommended by WHO as a first-line treatment for malaria in first trimester due to associated embryo-foetal toxicity in animal studies. The study assessed
New 4-amino-2-azabicyclo[3.2.2]nonane derivatives and their antiprotozoal potencies (Publications)
East African sleeping sickness, Trypanosoma b. rhodesiense, and a protozoan parasite which causes Malaria tropica, Plasmodium falciparum K-1, a strain which is resistant to chloroquine and pyrimethamine
Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort (Publications)
s in early pregnancy. They are, therefore, not recommended by WHO as a first-line treatment for malaria in first trimester due to associated embryo-foetal toxicity in animal studies. The study assessed
Long-lasting and fast-acting<em> in vivo</em> efficacious antiplasmodial azepanylcarbazole amino alcohol (Publications)
With approximately 429,000 deaths in 2016, malaria remains a major infectious disease where the need to treat the fever symptoms, but also to provide relevant post-treatment prophylaxis, is of major importance
Inhibitors of Plasmepsin II-potential antimalarial agents (Publications)
In order to overcome the problem of drug resistance in malaria, it appears wise to concentrate drug discovery efforts toward new structural classes and new mechanisms of action. We report our results,
Global Health at a Crossroads: Who Will Fill the Gap? (Blog)
https://www.swisstph.ch/en/impact-stories/global-health-at-a-crossroads-who-will-fill-the-gap/blog-id/102/blog-id/102
USAID funding freeze and shifting donor priorities are already disrupting essential programmes—from malaria elimination and HIV treatment to critical health system support. At Swiss TPH, we see the consequences
Inhibitors of Plasmepsin II-potential antimalarial agents (Publications)
In order to overcome the problem of drug resistance in malaria, it appears wise to concentrate drug discovery efforts toward new structural classes and new mechanisms of action. We report our results,
Long-lasting and fast-acting<em> in vivo</em> efficacious antiplasmodial azepanylcarbazole amino alcohol (Publications)
With approximately 429,000 deaths in 2016, malaria remains a major infectious disease where the need to treat the fever symptoms, but also to provide relevant post-treatment prophylaxis, is of major importance
DDT contamination in water resources of some African countries and its impact on water quality and human health (Publications)
use in indoor residual spraying (IRS) in developing countries, including African countries, for malaria control. There have been no previous reviews on DDT residues in water resources in Africa. The study [...] risk in sampled drinking sources within African water systems. Therefore, alternative methods for malaria vector control should be investigated and applied.
Activation of TCR Vδ1+ and Vδ1-Vδ2- γδ T cells upon controlled infection with <em>Plasmodium falciparum</em> in Tanzanian volunteers (Publications)
immune response to malaria remains incomplete. Clinical trials using whole-sporozoite-based vaccination approaches such as the Sanaria PfSPZ Vaccine, followed by controlled human malaria infection (CHMI)
